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    Gng10 G protein subunit gamma 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 114119, updated on 28-Oct-2024

    Summary

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    Symbol
    Gng10provided by RGD
    Full Name
    G protein subunit gamma 10provided by RGD
    Primary source
    RGD:621514
    See related
    EnsemblRapid:ENSRNOG00000025040 AllianceGenome:RGD:621514
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hg3m1
    Summary
    Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Part of heterotrimeric G-protein complex. Orthologous to human GNG10 (G protein subunit gamma 10). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in Liver (RPKM 425.2), Spleen (RPKM 413.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gng10 in Genome Data Viewer
    Location:
    5q24
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (78651167..78658060)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (73856124..73863017)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (76182100..76189014)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478984 Neighboring gene prostaglandin reductase 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C25 Neighboring gene U2 spliceosomal RNA Neighboring gene shortage in chiasmata 1 Neighboring gene uncharacterized LOC134486939 Neighboring gene uncharacterized LOC102550849

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Heterotypic tubular connections at the endoplasmic reticulum-Golgi complex interface. Vivero-Salmerón G, et al. Histochem Cell Biol, 2008 Oct. PMID 18648846
    2. Distribution of heterotrimeric G-protein beta and gamma subunits in the rat brain. Betty M, et al. Neuroscience, 1998 Jul. PMID 9622245
    3. Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Xiao HS, et al. Proc Natl Acad Sci U S A, 2002 Jun 11. PMID 12060780, Free PMC Article
    4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124511

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of heterotrimeric G-protein complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
    Names
    guanine nucleotide binding protein (G protein), gamma 10
    guanine nucleotide binding protein 10
    guanine nucleotide binding protein gamma 10 subunit
    heterotrimeric guanine nucleotide-binding protein 3m1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053660.2 → NP_446112.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10

      See identical proteins and their annotated locations for NP_446112.1

      Status: VALIDATED

      Source sequence(s)
      CB326556, CB616034, FQ214425
      UniProtKB/TrEMBL
      Q3KRE3
      Related
      ENSRNOP00000110602.1, ENSRNOT00000020707.9
      Conserved Domains (1) summary
      cd00068
      Location:7 → 63
      GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      78651167..78658060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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