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    Inositol 1,3,4-trisphosphate 5/6-kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829519, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Inositol 1,3,4-trisphosphate 5/6-kinase family protein
    Primary source
    TAIR:AT4G33770
    Locus tag
    AT4G33770
    See related
    Araport:AT4G33770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3; 4-trisphosphate 5/6 kinase 2; inositol 1; ITPK2; T16L1.260; T16L1_260
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    9
    Sequence:
    Chromosome: 4; NC_003075.7 (16193373..16196642, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene myb-like protein X Neighboring gene tRNA synthetase class II (D, K and N) family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP phosphoribosyltransferase regulatory subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis inositol 1,3,4-trisphosphate 5/6 kinase 2 is required for seed coat development. Tang Y, et al. Acta Biochim Biophys Sin (Shanghai), 2013 Jul. PMID 23595027
    2. INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-dependent inositol polyphosphates regulate auxin responses in Arabidopsis. Laha NP, et al. Plant Physiol, 2022 Nov 28. PMID 36124979, Free PMC Article
    3. Arabidopsis ITPK1 and ITPK2 Have an Evolutionarily Conserved Phytic Acid Kinase Activity. Laha D, et al. ACS Chem Biol, 2019 Oct 18. PMID 31525024
    4. Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis. Sweetman D, et al. FEBS Lett, 2007 Sep 4. PMID 17698066
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ITPK2 protein phosphorylates phytic acid to yield inositol heptakisphosphate.
      Title: Arabidopsis ITPK1 and ITPK2 Have an Evolutionarily Conserved Phytic Acid Kinase Activity.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001085021.2
    NM_001342232.1
    NM_119535.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inositol-1,3,4-trisphosphate 5-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol-1,3,4-trisphosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,3,4-trisphosphate 6-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol-1,3,4-trisphosphate 6-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-3,4,5,6-tetrakisphosphate 1-kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables inositol-3,4,5,6-tetrakisphosphate 1-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in auxin-activated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in inositol trisphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in seed coat development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Inositol 1,3,4-trisphosphate 5/6-kinase family protein
    NP_001078490.1
    • Inositol 1,3,4-trisphosphate 5/6-kinase family protein; FUNCTIONS IN: inositol or phosphatidylinositol kinase activity, magnesium ion binding, inositol-1,3,4-trisphosphate 5/6-kinase activity, inositol tetrakisphosphate 1-kinase activity, ATP binding; INVOLVED IN: inositol trisphosphate metabolic process; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Inositol-tetrakisphosphate 1-kinase (InterPro:IPR017427), Inositol 1, 3, 4-trisphosphate 56-kinase (InterPro:IPR008656); BEST Arabidopsis thaliana protein match is: Inositol 1,3,4-trisphosphate 5/6-kinase family protein (TAIR:AT4G08170.2); Has 392 Blast hits to 387 proteins in 76 species: Archae - 0; Bacteria - 0; Metazoa - 96; Fungi - 0; Plants - 249; Viruses - 0; Other Eukaryotes - 47 (source: NCBI BLink).
    NP_195103.3
    • Inositol 1,3,4-trisphosphate 5/6-kinase family protein; FUNCTIONS IN: inositol or phosphatidylinositol kinase activity, magnesium ion binding, inositol-1,3,4-trisphosphate 5/6-kinase activity, inositol tetrakisphosphate 1-kinase activity, ATP binding; INVOLVED IN: inositol trisphosphate metabolic process; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Inositol-tetrakisphosphate 1-kinase (InterPro:IPR017427), Inositol 1, 3, 4-trisphosphate 56-kinase (InterPro:IPR008656); BEST Arabidopsis thaliana protein match is: Inositol 1,3,4-trisphosphate 5/6-kinase family protein (TAIR:AT4G08170.2); Has 392 Blast hits to 387 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 96; Fungi - 0; Plants - 249; Viruses - 0; Other Eukaryotes - 47 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16193373..16196642 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119535.5 → NP_195103.3  Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195103.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81893, Q058I3
      UniProtKB/TrEMBL
      A0A178V3P3
      Conserved Domains (1) summary
      PLN02941
      Location:80 → 384
      PLN02941; inositol-tetrakisphosphate 1-kinase

    2. NM_001342232.1 → NP_001328707.1  Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V2A8, A0A1P8B5H0, A0A384KFJ1

    3. NM_001085021.2 → NP_001078490.1  Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078490.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MRH2
      Conserved Domains (1) summary
      PLN02941
      Location:12 → 291
      PLN02941; inositol-tetrakisphosphate 1-kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81893.3

    Gene LinkOut

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