Ank2 ankyrin 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Ank2provided by RGD
Full Name: ankyrin 2provided by RGD
Primary source: RGD:620156
See related: EnsemblRapid:ENSRNOG00000011076 AllianceGenome:RGD:620156
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ank3
Summary: Enables protein kinase binding activity and transmembrane transporter binding activity. A structural constituent of cytoskeleton. Involved in paranodal junction assembly and response to methylmercury. Predicted to be located in several cellular components, including T-tubule; basolateral plasma membrane; and myofibril. Predicted to be active in paranodal junction. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 503.8), Heart (RPKM 95.2) and 4 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q42

Exon count:: 58

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (218052555..218628414, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (215378028..215954015, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (231224643..231522655, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules.
Title: Giant ankyrin-B suppresses stochastic collateral axon branching through direct interaction with microtubules.
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes.
Title: Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes.
The identification and characterization of two functionally distinct ankyrin-B isoforms in heart provide compelling evidence that alternative splicing of the ANK2 gene regulates the fidelity of ankyrin-B interactions with proteins
Title: Identification and characterization of two ankyrin-B isoforms in mammalian heart.
Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons.
Title: Ankyrin-B structurally defines terminal microdomains of peripheral somatosensory axons.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BE101848 (e-PCR)
- UniSTS:243755

RH141556 (e-PCR)
- UniSTS:223550

WIAF-2193 (e-PCR)
- UniSTS:5702

RH144369 (e-PCR)
- UniSTS:233614

BF390514 (e-PCR)
- UniSTS:249489

RH132931 (e-PCR)
- UniSTS:216214

D2Rat360 (e-PCR)
- UniSTS:227494

AW491075 (e-PCR)
- UniSTS:178931

NIB1562 (e-PCR)
- UniSTS:13305

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATPase binding	ISO Inferred from Sequence Orthology more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables phosphorylation-dependent protein binding	ISO Inferred from Sequence Orthology more info
enables potassium channel regulator activity	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	ISO Inferred from Sequence Orthology more info
enables protein-macromolecule adaptor activity	ISO Inferred from Sequence Orthology more info
enables spectrin binding	ISO Inferred from Sequence Orthology more info
enables structural constituent of cytoskeleton	IDA Inferred from Direct Assay more info	PubMed
enables transmembrane transporter binding	IPI Inferred from Physical Interaction more info	PubMed
enables transmembrane transporter binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in SA node cell action potential	ISO Inferred from Sequence Orthology more info
involved_in SA node cell to atrial cardiac muscle cell communication	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within T-tubule organization	ISO Inferred from Sequence Orthology more info
involved_in T-tubule organization	ISO Inferred from Sequence Orthology more info
involved_in atrial cardiac muscle cell action potential	ISO Inferred from Sequence Orthology more info
involved_in atrial cardiac muscle cell to AV node cell communication	ISO Inferred from Sequence Orthology more info
involved_in atrial septum development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within cardiac muscle contraction	ISO Inferred from Sequence Orthology more info
involved_in cytoskeleton organization	IEA Inferred from Electronic Annotation more info
involved_in intracellular calcium ion homeostasis	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	IEP Inferred from Expression Pattern more info	PubMed
involved_in paranodal junction assembly	IEP Inferred from Expression Pattern more info	PubMed
involved_in positive regulation of calcium ion transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of calcium ion transport	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cation channel activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of potassium ion transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of potassium ion transport	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein localization	ISO Inferred from Sequence Orthology more info
involved_in protein localization	ISO Inferred from Sequence Orthology more info
involved_in protein localization to M-band	ISO Inferred from Sequence Orthology more info
involved_in protein localization to T-tubule	ISO Inferred from Sequence Orthology more info
involved_in protein localization to cell surface	ISO Inferred from Sequence Orthology more info
involved_in protein localization to endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
involved_in protein localization to organelle	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in protein localization to plasma membrane	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info
involved_in regulation of AV node cell action potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of SA node cell action potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of atrial cardiac muscle cell action potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of calcium ion transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
involved_in regulation of calcium ion transport	ISO Inferred from Sequence Orthology more info
involved_in regulation of cardiac muscle cell contraction	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of cardiac muscle cell membrane potential	ISO Inferred from Sequence Orthology more info
involved_in regulation of cardiac muscle contraction	ISO Inferred from Sequence Orthology more info
involved_in regulation of cardiac muscle contraction by calcium ion signaling	ISO Inferred from Sequence Orthology more info
involved_in regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within regulation of cation channel activity	ISO Inferred from Sequence Orthology more info
involved_in regulation of heart rate	ISO Inferred from Sequence Orthology more info
involved_in regulation of heart rate by cardiac conduction	ISO Inferred from Sequence Orthology more info
involved_in regulation of release of sequestered calcium ion into cytosol	ISO Inferred from Sequence Orthology more info
involved_in regulation of ventricular cardiac muscle cell membrane repolarization	ISO Inferred from Sequence Orthology more info
involved_in response to methylmercury	IEP Inferred from Expression Pattern more info	PubMed
involved_in ventricular cardiac muscle cell action potential	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in A band	ISO Inferred from Sequence Orthology more info
located_in M band	ISO Inferred from Sequence Orthology more info
located_in T-tubule	ISO Inferred from Sequence Orthology more info
located_in Z disc	ISO Inferred from Sequence Orthology more info
located_in basolateral plasma membrane	ISO Inferred from Sequence Orthology more info
located_in costamere	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in extrinsic component of cytoplasmic side of plasma membrane	ISO Inferred from Sequence Orthology more info
located_in intercalated disc	ISO Inferred from Sequence Orthology more info
is_active_in paranodal junction	ISO Inferred from Sequence Orthology more info
located_in perinuclear region of cytoplasm	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in postsynaptic density	ISO Inferred from Sequence Orthology more info
located_in sarcolemma	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ankyrin-2

Names: ankyrin 2, brain; ankyrin 2, neuronal; ankyrin 3, epithelial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001427159.1 → NP_001414088.1 ankyrin-2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

Related

ENSRNOP00000015386.10, ENSRNOT00000015386.11

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086020.1 Reference GRCr8

Range

218052555..218628414 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063282205.1 → XP_063138275.1 ankyrin-2 isoform X28
XM_063282210.1 → XP_063138280.1 ankyrin-2 isoform X35
XM_063282212.1 → XP_063138282.1 ankyrin-2 isoform X45

Related

ENSRNOP00000098357.2, ENSRNOT00000120732.2
XM_063282199.1 → XP_063138269.1 ankyrin-2 isoform X21

Related

ENSRNOP00000052477.7, ENSRNOT00000055615.8
XM_063282195.1 → XP_063138265.1 ankyrin-2 isoform X16
XM_063282185.1 → XP_063138255.1 ankyrin-2 isoform X5
XM_063282213.1 → XP_063138283.1 ankyrin-2 isoform X46
XM_039104008.2 → XP_038959936.1 ankyrin-2 isoform X8

Conserved Domains (9) summary

smart00218
Location:843 → 980

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PTZ00121
Location:1431 → 2195

PTZ00121; MAEBL; Provisional

PHA03095
Location:261 → 546

PHA03095; ankyrin-like protein; Provisional

PHA03307
Location:1580 → 1861

PHA03307; transcriptional regulator ICP4; Provisional

cd08804
Location:3436 → 3519

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:287 → 318

ANK; ANK repeat [structural motif]

pfam13637
Location:618 → 670

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1201 → 1330

UPA_2; UPA domain

cl39094
Location:418 → 642

Ank_2; Ankyrin repeats (3 copies)
XM_063282182.1 → XP_063138252.1 ankyrin-2 isoform X1
XM_063282202.1 → XP_063138272.1 ankyrin-2 isoform X24
XM_063282198.1 → XP_063138268.1 ankyrin-2 isoform X19
XM_039104025.2 → XP_038959953.1 ankyrin-2 isoform X34

Related

ENSRNOP00000073918.3, ENSRNOT00000080470.3

Conserved Domains (10) summary

smart00218
Location:798 → 902

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PTZ00121
Location:1353 → 2117

PTZ00121; MAEBL; Provisional

PHA03095
Location:87 → 392

PHA03095; ankyrin-like protein; Provisional

PHA03307
Location:1502 → 1783

PHA03307; transcriptional regulator ICP4; Provisional

cd08804
Location:3358 → 3441

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:295 → 326

ANK; ANK repeat [structural motif]

pfam13637
Location:593 → 645

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1123 → 1252

UPA_2; UPA domain

pfam12796
Location:1 → 130

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:342 → 617

Ank_2; Ankyrin repeats (3 copies)
XM_063282192.1 → XP_063138262.1 ankyrin-2 isoform X13
XM_039104019.2 → XP_038959947.1 ankyrin-2 isoform X20

Conserved Domains (10) summary

smart00218
Location:831 → 935

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PTZ00121
Location:1386 → 2150

PTZ00121; MAEBL; Provisional

PHA03095
Location:269 → 554

PHA03095; ankyrin-like protein; Provisional

PHA03307
Location:1535 → 1816

PHA03307; transcriptional regulator ICP4; Provisional

cd08804
Location:3391 → 3474

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:295 → 326

ANK; ANK repeat [structural motif]

pfam13637
Location:626 → 678

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1156 → 1285

UPA_2; UPA domain

pfam12796
Location:1 → 130

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:426 → 650

Ank_2; Ankyrin repeats (3 copies)
XM_063282193.1 → XP_063138263.1 ankyrin-2 isoform X14
XM_063282186.1 → XP_063138256.1 ankyrin-2 isoform X6
XM_063282197.1 → XP_063138267.1 ankyrin-2 isoform X18
XM_063282187.1 → XP_063138257.1 ankyrin-2 isoform X7
XM_039103998.2 → XP_038959926.1 ankyrin-2 isoform X2

Conserved Domains (10) summary

smart00218
Location:861 → 998

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PTZ00121
Location:1449 → 2213

PTZ00121; MAEBL; Provisional

PHA03095
Location:269 → 554

PHA03095; ankyrin-like protein; Provisional

PHA03307
Location:1598 → 1879

PHA03307; transcriptional regulator ICP4; Provisional

cd08804
Location:3454 → 3537

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:295 → 326

ANK; ANK repeat [structural motif]

pfam13637
Location:626 → 678

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1219 → 1348

UPA_2; UPA domain

pfam12796
Location:1 → 130

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:426 → 650

Ank_2; Ankyrin repeats (3 copies)
XM_063282191.1 → XP_063138261.1 ankyrin-2 isoform X12
XM_063282209.1 → XP_063138279.1 ankyrin-2 isoform X33
XM_063282208.1 → XP_063138278.1 ankyrin-2 isoform X31
XM_063282189.1 → XP_063138259.1 ankyrin-2 isoform X10
XM_063282206.1 → XP_063138276.1 ankyrin-2 isoform X29
XM_063282184.1 → XP_063138254.1 ankyrin-2 isoform X4
XM_063282204.1 → XP_063138274.1 ankyrin-2 isoform X26
XM_063282217.1 → XP_063138287.1 ankyrin-2 isoform X50
XM_063282207.1 → XP_063138277.1 ankyrin-2 isoform X30
XM_039104045.2 → XP_038959973.1 ankyrin-2 isoform X43

Conserved Domains (7) summary

smart00218
Location:933 → 1037

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

cd08804
Location:1416 → 1499

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:728 → 780

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1258 → 1387

UPA_2; UPA domain

pfam12796
Location:402 → 493

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:477 → 752

Ank_2; Ankyrin repeats (3 copies)
XM_039104044.2 → XP_038959972.1 ankyrin-2 isoform X42

Conserved Domains (7) summary

smart00218
Location:945 → 1049

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

cd08804
Location:1428 → 1511

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:728 → 780

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1270 → 1399

UPA_2; UPA domain

pfam12796
Location:402 → 493

Ank_2; Ankyrin repeats (3 copies)

cl39094
Location:477 → 752

Ank_2; Ankyrin repeats (3 copies)
XM_063282200.1 → XP_063138270.1 ankyrin-2 isoform X22
XM_039104042.2 → XP_038959970.1 ankyrin-2 isoform X41

Conserved Domains (7) summary

smart00218
Location:966 → 1070

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PHA03095
Location:404 → 689

PHA03095; ankyrin-like protein; Provisional

cd08804
Location:1449 → 1532

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:761 → 813

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1291 → 1420

UPA_2; UPA domain

cl39094
Location:561 → 785

Ank_2; Ankyrin repeats (3 copies)
XM_039104040.2 → XP_038959968.1 ankyrin-2 isoform X40

Conserved Domains (7) summary

smart00218
Location:966 → 1070

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PHA03095
Location:404 → 689

PHA03095; ankyrin-like protein; Provisional

cd08804
Location:1449 → 1532

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:761 → 813

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1291 → 1420

UPA_2; UPA domain

cl39094
Location:561 → 785

Ank_2; Ankyrin repeats (3 copies)
XM_039104023.2 → XP_038959951.1 ankyrin-2 isoform X32

UniProtKB/TrEMBL

A0A0G2K6R9

Related

ENSRNOP00000035307.7, ENSRNOT00000037255.8

Conserved Domains (9) summary

smart00218
Location:966 → 1070

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PTZ00121
Location:1521 → 2285

PTZ00121; MAEBL; Provisional

PHA03095
Location:404 → 689

PHA03095; ankyrin-like protein; Provisional

PHA03307
Location:1670 → 1951

PHA03307; transcriptional regulator ICP4; Provisional

cd08804
Location:3526 → 3609

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:761 → 813

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1291 → 1420

UPA_2; UPA domain

cl39094
Location:561 → 785

Ank_2; Ankyrin repeats (3 copies)
XM_039104038.2 → XP_038959966.1 ankyrin-2 isoform X39

Conserved Domains (7) summary

smart00218
Location:966 → 1103

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PHA03095
Location:404 → 689

PHA03095; ankyrin-like protein; Provisional

cd08804
Location:1482 → 1565

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:761 → 813

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1324 → 1453

UPA_2; UPA domain

cl39094
Location:561 → 785

Ank_2; Ankyrin repeats (3 copies)
XM_063282215.1 → XP_063138285.1 ankyrin-2 isoform X48
XM_039104022.2 → XP_038959950.1 ankyrin-2 isoform X27

UniProtKB/TrEMBL

A0A0G2K6R9

Conserved Domains (9) summary

smart00218
Location:966 → 1103

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PTZ00121
Location:1554 → 2318

PTZ00121; MAEBL; Provisional

PHA03095
Location:404 → 689

PHA03095; ankyrin-like protein; Provisional

PHA03307
Location:1703 → 1984

PHA03307; transcriptional regulator ICP4; Provisional

cd08804
Location:3559 → 3642

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:761 → 813

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1324 → 1453

UPA_2; UPA domain

cl39094
Location:561 → 785

Ank_2; Ankyrin repeats (3 copies)
XM_039104031.2 → XP_038959959.1 ankyrin-2 isoform X37

Conserved Domains (7) summary

smart00218
Location:978 → 1115

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PHA03095
Location:404 → 689

PHA03095; ankyrin-like protein; Provisional

cd08804
Location:1494 → 1577

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:430 → 461

ANK; ANK repeat [structural motif]

pfam13637
Location:761 → 813

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1336 → 1465

UPA_2; UPA domain

cl39094
Location:561 → 785

Ank_2; Ankyrin repeats (3 copies)
XM_063282194.1 → XP_063138264.1 ankyrin-2 isoform X15
XM_063282188.1 → XP_063138258.1 ankyrin-2 isoform X9
XM_063282211.1 → XP_063138281.1 ankyrin-2 isoform X44
XM_063282201.1 → XP_063138271.1 ankyrin-2 isoform X23
XM_063282203.1 → XP_063138273.1 ankyrin-2 isoform X25
XM_039104034.2 → XP_038959962.1 ankyrin-2 isoform X38

Conserved Domains (7) summary

smart00218
Location:981 → 1118

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PHA03095
Location:419 → 704

PHA03095; ankyrin-like protein; Provisional

cd08804
Location:1497 → 1580

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:445 → 476

ANK; ANK repeat [structural motif]

pfam13637
Location:776 → 828

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1339 → 1468

UPA_2; UPA domain

cl39094
Location:576 → 800

Ank_2; Ankyrin repeats (3 copies)
XM_039104029.2 → XP_038959957.1 ankyrin-2 isoform X36

Conserved Domains (7) summary

smart00218
Location:981 → 1118

ZU5; Domain present in ZO-1 and Unc5-like netrin receptors

PHA03095
Location:419 → 704

PHA03095; ankyrin-like protein; Provisional

cd08804
Location:1497 → 1580

Death_ank2; Death domain of Ankyrin-2

sd00045
Location:445 → 476

ANK; ANK repeat [structural motif]

pfam13637
Location:776 → 828

Ank_4; Ankyrin repeats (many copies)

pfam17809
Location:1339 → 1468

UPA_2; UPA domain

cl39094
Location:576 → 800

Ank_2; Ankyrin repeats (3 copies)
XM_063282196.1 → XP_063138266.1 ankyrin-2 isoform X17

Related

ENSRNOP00000075511.3, ENSRNOT00000084756.3
XM_063282214.1 → XP_063138284.1 ankyrin-2 isoform X47
XM_063282216.1 → XP_063138286.1 ankyrin-2 isoform X49
XM_063282190.1 → XP_063138260.1 ankyrin-2 isoform X11
XM_063282183.1 → XP_063138253.1 ankyrin-2 isoform X3