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    Trnp1 TMF1-regulated nuclear protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 688990, updated on 18-Sep-2024

    Summary

    Symbol
    Trnp1provided by RGD
    Full Name
    TMF1-regulated nuclear protein 1provided by RGD
    Primary source
    RGD:1582917
    See related
    EnsemblRapid:ENSRNOG00000055936 AllianceGenome:RGD:1582917
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in several processes, including cerebellar cortex morphogenesis; neural precursor cell proliferation; and regulation of cell population proliferation. Predicted to be located in nucleus. Predicted to colocalize with euchromatin. Orthologous to human TRNP1 (TMF1 regulated nuclear protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 132.1), Heart (RPKM 25.1) and 2 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Trnp1 in Genome Data Viewer
    Location:
    5q36
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (150990312..150997148, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (145706427..145713279, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (151703139..151709988, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479037 Neighboring gene terminal nucleotidyltransferase 5B Neighboring gene uncharacterized LOC120103102 Neighboring gene keratinocyte differentiation factor 1 Neighboring gene nuclear distribution C, dynein complex regulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cerebellar cortex morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neural precursor cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in euchromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    TMF-regulated nuclear protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001402229.1NP_001389158.1  TMF-regulated nuclear protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A0G2K0Y1
      Related
      ENSRNOP00000089751.1, ENSRNOT00000097339.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      150990312..150997148 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001069068.8XP_001069068.5  TMF-regulated nuclear protein 1 isoform X1

      See identical proteins and their annotated locations for XP_001069068.5

      UniProtKB/TrEMBL
      A0A0G2K0Y1
      Related
      ENSRNOP00000071624.1, ENSRNOT00000080602.3
      Conserved Domains (1) summary
      cl22856
      Location:108169
      SNARE; SNARE motif