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    Sys1 Sys1 golgi trafficking protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685079, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Sys1provided by RGD
    Official Full Name
    Sys1 golgi trafficking proteinprovided by RGD
    Primary source
    RGD:1583224
    See related
    EnsemblRapid:ENSRNOG00000014480 AllianceGenome:RGD:1583224
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in Golgi to endosome transport; Golgi to plasma membrane protein transport; and protein localization to Golgi apparatus. Predicted to be located in cytosol. Predicted to be active in trans-Golgi network. Predicted to be integral component of Golgi membrane. Orthologous to human SYS1 (SYS1 golgi trafficking protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 80.1), Kidney (RPKM 79.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sys1 in Genome Data Viewer
    Location:
    3q42
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (173610332..173637624)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (153191061..153195463)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (160908779..160913281)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene matrilin 4 Neighboring gene recombination signal binding protein for immunoglobulin kappa J region-like Neighboring gene syndecan 4 Neighboring gene TP53 target 5 Neighboring gene dysbindin domain containing 2 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class T Neighboring gene uncharacterized LOC120101784

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi to endosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein SYS1 homolog
    Names
    SYS1 Golgi-localized integral membrane protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399565.1 → NP_001386494.1  protein SYS1 homolog

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6JX85, D3ZY25
      Related
      ENSRNOP00000037520.4, ENSRNOT00000030054.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      173610332..173637624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284553.1 → XP_063140623.1  protein SYS1 homolog isoform X1

      UniProtKB/TrEMBL
      A6JX84

    2. XM_063284554.1 → XP_063140624.1  protein SYS1 homolog isoform X2

      UniProtKB/TrEMBL
      A6JX83, A6JX84
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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