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    Pim2 Pim-2 proto-oncogene, serine/threonine kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317366, updated on 10-Jul-2024

    Summary

    Gene symbol
    Pim2
    Gene description
    Pim-2 proto-oncogene, serine/threonine kinase
    See related
    EnsemblRapid:ENSRNOG00000008177
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Brain (RPKM 55.6), Spleen (RPKM 35.3) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Pim2 in Genome Data Viewer
    Location:
    Xq12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (17289509..17294778, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (14617582..14622851, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (15462621..15467890, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene polyglutamine binding protein 1 Neighboring gene solute carrier family 35 member A2 Neighboring gene OTU deubiquitinase 5 Neighboring gene solute carrier family 25 member 39, pseudogene 6 Neighboring gene potassium voltage-gated channel subfamily D member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    serine/threonine-protein kinase pim-2
    Names
    pim-2 oncogene
    NP_001165574.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001172103.1NP_001165574.1  serine/threonine-protein kinase pim-2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6KP72, F1M419
      Related
      ENSRNOP00000011207.6, ENSRNOT00000011207.9
      Conserved Domains (2) summary
      smart00220
      Location:32286
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:31287
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      17289509..17294778 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)