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    Cnot11 CCR4-NOT transcription complex, subunit 11 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363221, updated on 10-Jul-2024

    Summary

    Official Symbol
    Cnot11provided by RGD
    Official Full Name
    CCR4-NOT transcription complex, subunit 11provided by RGD
    Primary source
    RGD:1560909
    See related
    EnsemblRapid:ENSRNOG00000023220 AllianceGenome:RGD:1560909
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560909
    Summary
    Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of CCR4-NOT complex. Orthologous to human CNOT11 (CCR4-NOT transcription complex subunit 11). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 75.1), Spleen (RPKM 51.3) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cnot11 in Genome Data Viewer
    Location:
    9q22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (49310624..49320325)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (41814923..41824626)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (46270229..46279928)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L31 Neighboring gene TBC1 domain family, member 8 Neighboring gene uncharacterized LOC134480362 Neighboring gene ring finger protein 149, pseudogene 2 Neighboring gene small nucleolar RNA, C/D box 89 Neighboring gene ring finger protein 149

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulatory ncRNA-mediated gene silencing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of CCR4-NOT complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of CCR4-NOT complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of CCR4-NOT complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    CCR4-NOT transcription complex subunit 11
    Names
    UPF0760 protein C2orf29 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108794.2NP_001102264.1  CCR4-NOT transcription complex subunit 11

      See identical proteins and their annotated locations for NP_001102264.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158750
      UniProtKB/Swiss-Prot
      B0BNA9
      Related
      ENSRNOP00000035943.5, ENSRNOT00000031352.7
      Conserved Domains (1) summary
      pfam10155
      Location:365489
      DUF2363; Uncharacterized conserved protein (DUF2363)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      49310624..49320325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063267372.1XP_063123442.1  CCR4-NOT transcription complex subunit 11 isoform X1