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    FMP25 Fmp25p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850766, updated on 2-Nov-2024

    Summary

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    Official Symbol
    FMP25
    Official Full Name
    Fmp25p
    Primary source
    SGD:S000004067
    Locus tag
    YLR077W
    See related
    AllianceGenome:SGD:S000004067; FungiDB:YLR077W; VEuPathDB:YLR077W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    BCA1
    Summary
    Involved in mitochondrial respiratory chain complex III assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See FMP25 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (283872..285623)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Bud20p Neighboring gene ribosomal 60S subunit protein L10 Neighboring gene Bos1p Neighboring gene cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A transcriptome screen in yeast identifies a novel assembly factor for the mitochondrial complex III. Mathieu L, et al. Mitochondrion, 2011 May. PMID 21168530
    2. The Cbp3-Cbp6 complex coordinates cytochrome b synthesis with bc(1) complex assembly in yeast mitochondria. Gruschke S, et al. J Cell Biol, 2012 Oct 1. PMID 23007649, Free PMC Article
    3. Molecular Wiring of a Mitochondrial Translational Feedback Loop. Salvatori R, et al. Mol Cell, 2020 Feb 20. PMID 31883951
    4. Evaluation of genes involved in oxidative phosphorylation in yeast by developing a simple and rapid method to measure mitochondrial ATP synthetic activity. Ye X, et al. Microb Cell Fact, 2015 Apr 16. PMID 25880855, Free PMC Article
    5. Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Vukotic M, et al. Cell Metab, 2012 Mar 7. PMID 22342701

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex III assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial respiratory chain complex III assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fmp25p
    NP_013178.1
    • Protein required for assembly of respiratory complex III; mitochondrial inner membrane protein; required for an early step in assembly of respiratory complex III (cytochrome bc1 complex); mRNA is targeted to mitochondria

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      283872..285623
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181964.1 → NP_013178.1  TPA: Fmp25p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013178.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY77, Q08023, Q66R51, Q7LI62
      UniProtKB/TrEMBL
      A7A0Y1, C8ZD48, G2WIR8
      Conserved Domains (1) summary
      COG5184
      Location:8 → 577
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08023.1

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