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    Tmem150a transmembrane protein 150A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 245966, updated on 10-Jul-2024

    Summary

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    Official Symbol
    Tmem150aprovided by RGD
    Official Full Name
    transmembrane protein 150Aprovided by RGD
    Primary source
    RGD:619998
    See related
    EnsemblRapid:ENSRNOG00000061100 AllianceGenome:RGD:619998
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tm6p1; Tmem150
    Summary
    Involved in catabolic process. Is integral component of membrane. Orthologous to human TMEM150A (transmembrane protein 150A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Liver (RPKM 475.5), Kidney (RPKM 407.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem150a in Genome Data Viewer
    Location:
    4q32
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (105968526..105972822)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (104410271..104414630)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (100217986..100222131)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene surfactant protein B Neighboring gene ubiquitin specific peptidase 39 Neighboring gene similar to human chromosome 2 open reading frame 68 Neighboring gene ring finger protein 181 Neighboring gene vesicle-associated membrane protein 5 Neighboring gene uncharacterized LOC134486592 Neighboring gene vesicle-associated membrane protein 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification of a new gene (rat TM6P1) encoding a fasting-inducible, integral membrane protein with six transmembrane domains. Zhang J, et al. Biochim Biophys Acta, 2000 Jun 21. PMID 10858565
    2. Plasticity of PI4KIIIα interactions at the plasma membrane. Chung J, et al. EMBO Rep, 2015 Mar. PMID 25608530, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in catabolic process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in phosphatidylinositol phosphate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein localization to plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 150A
    Names
    fasting-inducible integral membrane protein TM6P1
    transmembrane protein 150

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139107.1 → NP_620807.1  transmembrane protein 150A precursor

      See identical proteins and their annotated locations for NP_620807.1

      Status: PROVISIONAL

      Source sequence(s)
      AF186469
      UniProtKB/Swiss-Prot
      Q9QZE9
      UniProtKB/TrEMBL
      A0A8I6APK8, A6IAA6
      Conserved Domains (1) summary
      pfam10277
      Location:3 → 229
      Frag1; Frag1/DRAM/Sfk1 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      105968526..105972822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063285524.1 → XP_063141594.1  transmembrane protein 150A isoform X1

      UniProtKB/Swiss-Prot
      Q9QZE9
      UniProtKB/TrEMBL
      A0A8I6APK8, A6IAA6
      Related
      ENSRNOP00000110592.1, ENSRNOT00000172521.1

    2. XM_006236658.5 → XP_006236720.1  transmembrane protein 150A isoform X1

      See identical proteins and their annotated locations for XP_006236720.1

      UniProtKB/Swiss-Prot
      Q9QZE9
      UniProtKB/TrEMBL
      A0A8I6APK8, A6IAA6
      Conserved Domains (1) summary
      pfam10277
      Location:3 → 229
      Frag1; Frag1/DRAM/Sfk1 family

    3. XM_063285525.1 → XP_063141595.1  transmembrane protein 150A isoform X3

      UniProtKB/TrEMBL
      A0A8I6APK8
      Related
      ENSRNOP00000073089.2, ENSRNOT00000079415.3

    4. XM_017592444.3 → XP_017447933.2  transmembrane protein 150A isoform X2

      UniProtKB/TrEMBL
      A0A8I6APK8
      Conserved Domains (1) summary
      pfam10277
      Location:62 → 228
      Frag1; Frag1/DRAM/Sfk1 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QZE9.1 GenPept UniProtKB/Swiss-Prot:Q9QZE9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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