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    OXER1 oxoeicosanoid receptor 1 [ Homo sapiens (human) ]

    Gene ID: 165140, updated on 2-Nov-2024

    Summary

    Official Symbol
    OXER1provided by HGNC
    Official Full Name
    oxoeicosanoid receptor 1provided by HGNC
    Primary source
    HGNC:HGNC:24884
    See related
    Ensembl:ENSG00000162881 MIM:620064; AllianceGenome:HGNC:24884
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GPCR; GPR170; TG1019
    Summary
    Enables G protein-coupled receptor activity and icosanoid binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See OXER1 in Genome Data Viewer
    Location:
    2p21
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (42762499..42764135, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (42767768..42769404, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (42989639..42991275, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene metastasis associated 1 family member 3 Neighboring gene uncharacterized LOC105374555 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:42833249-42834000 Neighboring gene MPRA-validated peak3682 silencer Neighboring gene NANOG hESC enhancer GRCh37_chr2:42881137-42881638 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15651 Neighboring gene Sharpr-MPRA regulatory region 10188 Neighboring gene RNA, U6 small nuclear 137, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:42983755-42984326 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:42983184-42983754 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:42994558-42995463 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11411 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11412 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11413 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15652 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15653 Neighboring gene 3-hydroxyanthranilate 3,4-dioxygenase Neighboring gene FTO pseudogene 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    oxoeicosanoid receptor 1
    Names
    5-oxo-ETE G-protein coupled receptor
    5-oxo-ETE acid G-protein-coupled receptor 1
    G-protein coupled receptor 170
    G-protein coupled receptor R527
    G-protein coupled receptor TG1019
    OXE receptor
    oxoeicosanoid (OXE) receptor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_148962.5NP_683765.2  oxoeicosanoid receptor 1

      Status: VALIDATED

      Source sequence(s)
      AC098824
      Consensus CDS
      CCDS1810.2
      UniProtKB/Swiss-Prot
      Q86WP7, Q8NGW4, Q8TDS5
      Related
      ENSP00000367930.3, ENST00000378661.4
      Conserved Domains (1) summary
      cd15200
      Location:54327
      7tmA_OXER1; oxoeicosanoid receptor 1, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      42762499..42764135 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      42767768..42769404 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)