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    CBK1 serine/threonine protein kinase CBK1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855561, updated on 28-Oct-2024

    Summary

    Official Symbol
    CBK1
    Official Full Name
    serine/threonine protein kinase CBK1
    Primary source
    SGD:S000005105
    Locus tag
    YNL161W
    See related
    AllianceGenome:SGD:S000005105; FungiDB:YNL161W; VEuPathDB:YNL161W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein serine/threonine kinase activity. Involved in several processes, including budding cell apical bud growth; establishment or maintenance of actin cytoskeleton polarity; and regulation of fungal-type cell wall organization. Located in several cellular components, including cellular bud tip; incipient cellular bud site; and mating projection tip. Orthologous to several human genes including STK38 (serine/threonine kinase 38). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

    See CBK1 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (332597..334867)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ribosomal 60S subunit protein L42A Neighboring gene Ygp1p Neighboring gene Asi2p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine protein kinase CBK1
    NP_014238.3
    • Serine/threonine protein kinase of the the RAM signaling network; Ndr/LATS family member; binds regulatory subunit Mob2p; involved in regulation of cellular morphogenesis, polarized growth, and septum destruction; phosphorylation by Cbk1p regulates localization and activity of Ace2p transcription factor and Ssd1p translational repressor; Cbk1p activity is regulated by both phosphorylation and specific localization; relocalizes to cytoplasm upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      332597..334867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182999.3NP_014238.3  TPA: serine/threonine protein kinase CBK1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014238.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W122, P53894
      UniProtKB/TrEMBL
      A6ZRS3, G2WLU6, N1NXC7
      Conserved Domains (1) summary
      cd05629
      Location:350748
      STKc_NDR_like_fungal; Catalytic domain of Fungal Nuclear Dbf2-Related kinase-like Serine/Threonine Kinases