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    RPL16B ribosomal 60S subunit protein L16B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855655, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPL16B
    Official Full Name
    ribosomal 60S subunit protein L16B
    Primary source
    SGD:S000005013
    Locus tag
    YNL069C
    See related
    AllianceGenome:SGD:S000005013; FungiDB:YNL069C; VEuPathDB:YNL069C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    RP23
    Summary
    Enables RNA binding activity. Involved in maturation of LSU-rRNA. Part of cytosolic large ribosomal subunit. Is active in nucleolus. Orthologous to human RPL13A (ribosomal protein L13a). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL16B in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    2
    Sequence:
    Chromosome: XIV; NC_001146.8 (493956..495001, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene dihydrolipoyllysine-residue acetyltransferase Neighboring gene Tom7p Neighboring gene forkhead family transcription factor FKH2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of the yeast ribosomal protein L16 in ribosome biogenesis. Espinar-Marchena FJ, et al. FEBS J, 2016 Aug. PMID 27374275
    2. Ribosomal protein L14 contributes to the early assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. Espinar-Marchena F, et al. Nucleic Acids Res, 2018 May 18. PMID 29788267, Free PMC Article
    3. Identification of NAD+ capped mRNAs in Saccharomyces cerevisiae. Walters RW, et al. Proc Natl Acad Sci U S A, 2017 Jan 17. PMID 28031484, Free PMC Article
    4. Affinity purification of ribosomes to access the translatome. Halbeisen RE, et al. Methods, 2009 Jul. PMID 19398006
    5. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Chan CT, et al. Nat Commun, 2012 Jul 3. PMID 22760636, Free PMC Article

    See all (127) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in maturation of LSU-rRNA IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L16B
    NP_014330.1
    • Ribosomal 60S subunit protein L16B; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16B has a paralog, RPL16A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      493956..495001 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182907.1 → NP_014330.1  TPA: ribosomal 60S subunit protein L16B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014330.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1B0, P26785
      UniProtKB/TrEMBL
      B3LNS8, C8ZGG1, N1NXJ3
      Conserved Domains (1) summary
      PTZ00068
      Location:1 → 198
      PTZ00068; 60S ribosomal protein L13a; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P26785.3

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