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    RPS22B ribosomal 40S subunit protein S22B [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851082, updated on 29-Jun-2024

    Summary

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    Gene symbol
    RPS22B
    Gene description
    ribosomal 40S subunit protein S22B
    Primary source
    FungiDB:YLR367W
    Locus tag
    YLR367W
    See related
    SGD:S000004359; AllianceGenome:SGD:S000004359; VEuPathDB:YLR367W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 20. Orthologous to human RPS15A (ribosomal protein S15a). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPS22B in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    2
    Sequence:
    Chromosome: XII; NC_001144.5 (856442..857317)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene glutathione-disulfide reductase GRX8 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene SCF ubiquitin ligase complex subunit MDM30 Neighboring gene Hsp70 family ATPase SSQ1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Autoregulation of yeast ribosomal proteins discovered by efficient search for feedback regulation. Roy B, et al. Commun Biol, 2020 Dec 11. PMID 33311538, Free PMC Article
    2. Nuclear and nucleolar localization of Saccharomyces cerevisiae ribosomal proteins S22 and S25. Timmers AC, et al. FEBS Lett, 1999 Jun 11. PMID 10386617
    3. Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. Visweswaraiah J, et al. J Biol Chem, 2012 Nov 2. PMID 22888004, Free PMC Article
    4. Widespread impact of nonsense-mediated mRNA decay on the yeast intronome. Sayani S, et al. Mol Cell, 2008 Aug 8. PMID 18691968, Free PMC Article
    5. Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity. Visweswaraiah J, et al. J Biol Chem, 2011 Oct 21. PMID 21849502, Free PMC Article

    See all (60) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 40S subunit protein S22B
    NP_013471.1
    • Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22B has a paralog, RPS22A, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      856442..857317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182256.1 → NP_013471.1  TPA: ribosomal 40S subunit protein S22B [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013471.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ04, Q3E7Y3
      UniProtKB/TrEMBL
      A7A1P4, B3RHN4, C7GRW1, C8ZDX7, G2WJI4, N1P034
      Conserved Domains (1) summary
      PTZ00158
      Location:1 → 130
      PTZ00158; 40S ribosomal protein S15A; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3E7Y3.3

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