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    GFD2 Gfd2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850321, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GFD2
    Official Full Name
    Gfd2p
    Primary source
    SGD:S000000541
    Locus tag
    YCL036W
    See related
    AllianceGenome:SGD:S000000541; FungiDB:YCL036W; VEuPathDB:YCL036W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YCD6
    Summary
    Predicted to enable nucleic acid binding activity. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See GFD2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (59026..60726)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Atg22p Neighboring gene Sro9p Neighboring gene dithiol glutaredoxin GRX1 Neighboring gene Lsb5p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ssd1 is required for thermotolerance and Hsp104-mediated protein disaggregation in Saccharomyces cerevisiae. Mir SS, et al. Mol Cell Biol, 2009 Jan. PMID 18936161, Free PMC Article
    2. An early function during transcription for the yeast mRNA export factor Dbp5p/Rat8p suggested by its genetic and physical interactions with transcription factor IIH components. Estruch F, et al. Mol Biol Cell, 2003 Apr. PMID 12686617, Free PMC Article
    3. TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae. Alfatah M, et al. BMC Biol, 2021 May 6. PMID 33957926, Free PMC Article
    4. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
    5. A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Bon E, et al. Yeast, 2000 Sep 30. PMID 10992286

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Gfd2p
    NP_009894.1
    • hypothetical protein; identified as a high-copy suppressor of a dbp5 mutation; GFD2 has a paralog, YDR514C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      59026..60726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178681.1 → NP_009894.1  TPA: Gfd2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009894.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQX9, P25370
      UniProtKB/TrEMBL
      B3LU46, B5VES4
      Conserved Domains (1) summary
      cl10012
      Location:380 → 475
      DnaQ_like_exo; DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25370.1

    Gene LinkOut

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