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    FIT1 Fit1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852147, updated on 17-May-2024

    Summary

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    Gene symbol
    FIT1
    Gene description
    Fit1p
    Primary source
    FungiDB:YDR534C
    Locus tag
    YDR534C
    See related
    SGD:S000002942; AllianceGenome:SGD:S000002942; VEuPathDB:YDR534C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable ATP binding activity. Involved in siderophore transport. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See FIT1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1503314..1504900, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Kre28p Neighboring gene glutathione-independent methylglyoxalase Neighboring gene glucose-inactivated glycerol proton symporter STL1 Neighboring gene phenylacrylic acid decarboxylase PAD1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The localization change of Ybr078w/Ecm33, a yeast GPI-associated protein, from the plasma membrane to the cell wall, affecting the cellular function. Terashima H, et al. FEMS Microbiol Lett, 2003 Jan 21. PMID 12583915
    2. Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae. Protchenko O, et al. J Biol Chem, 2001 Dec 28. PMID 11673473
    3. Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. Foury F, et al. J Biol Chem, 2001 Mar 16. PMID 11112771
    4. The response to iron deprivation in Saccharomyces cerevisiae: expression of siderophore-based systems of iron uptake. Philpott CC, et al. Biochem Soc Trans, 2002 Aug. PMID 12196168
    5. Laboratory evolution of new lactate transporter genes in a jen1Δ mutant of Saccharomyces cerevisiae and their identification as ADY2 alleles by whole-genome resequencing and transcriptome analysis. de Kok S, et al. FEMS Yeast Res, 2012 May. PMID 22257278

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in iron ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in siderophore transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in siderophore transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fit1p
    NP_010823.1
    • Mannoprotein that is incorporated into the cell wall; incorporated via a glycosylphosphatidylinositol (GPI) anchor; involved in the retention of siderophore-iron in the cell wall

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1503314..1504900 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180842.1 → NP_010823.1  TPA: Fit1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010823.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTF5, Q04433
      UniProtKB/TrEMBL
      A0A8H8UP63, G2WBR1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04433.1

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