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    SPO74 Spo74p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852705, updated on 29-Jun-2024

    Summary

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    Gene symbol
    SPO74
    Gene description
    Spo74p
    Primary source
    FungiDB:YGL170C
    Locus tag
    YGL170C
    See related
    SGD:S000003138; AllianceGenome:SGD:S000003138; VEuPathDB:YGL170C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables structural molecule activity. Involved in ascospore formation. Located in meiotic spindle pole body. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SPO74 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (184153..185394, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene FG-nucleoporin NUP49 Neighboring gene RNA-dependent ATPase ROK1 Neighboring gene tRNA-Lys Neighboring gene threonylcarbamoyladenylate synthase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system. Taxis C, et al. J Cell Biol, 2005 Nov 21. PMID 16286509, Free PMC Article
    2. Membrane assembly modulates the stability of the meiotic spindle-pole body. Mathieson EM, et al. J Cell Sci, 2010 Jul 15. PMID 20592185, Free PMC Article
    3. Regulation of spindle pole function by an intermediary metabolite. Nickas ME, et al. Mol Biol Cell, 2004 Jun. PMID 15034143, Free PMC Article
    4. Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae. Nickas ME, et al. Eukaryot Cell, 2003 Jun. PMID 12796288, Free PMC Article
    5. A refined two-hybrid system reveals that SCF(Cdc4)-dependent degradation of Swi5 contributes to the regulatory mechanism of S-phase entry. Kishi T, et al. Proc Natl Acad Sci U S A, 2008 Sep 23. PMID 18787112, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural molecule activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural molecule activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ascospore formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in meiotic spindle pole body IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in spindle pole body HDA PubMed 
    located_in spindle pole body IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Spo74p
    NP_011345.3
    • Component of the meiotic outer plaque of the spindle pole body; involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      184153..185394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181035.3 → NP_011345.3  TPA: Spo74p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011345.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTY2, E9P8T5, P45819
      UniProtKB/TrEMBL
      A0A8H4C073, A6ZU16, N1P2W7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P45819.1

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