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    PEX31 peroxisome biogenesis protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852887, updated on 29-Jun-2024

    Summary

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    Gene symbol
    PEX31
    Gene description
    peroxisome biogenesis protein
    Primary source
    FungiDB:YGR004W
    Locus tag
    YGR004W
    See related
    SGD:S000003236; AllianceGenome:SGD:S000003236; VEuPathDB:YGR004W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in peroxisome organization and regulation of peroxisome organization. Is integral component of peroxisomal membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PEX31 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (502938..504326)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Swc4p Neighboring gene cullin CUL3 Neighboring gene transcription factor IIF subunit TFG2 Neighboring gene mRNA splicing protein PRP18

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A family of membrane-shaping proteins at ER subdomains regulates pre-peroxisomal vesicle biogenesis. Joshi AS, et al. J Cell Biol, 2016 Nov 21. PMID 27872254, Free PMC Article
    2. Production of the Fragrance Geraniol in Peroxisomes of a Product-Tolerant Baker's Yeast. Gerke J, et al. Front Bioeng Biotechnol, 2020. PMID 33102464, Free PMC Article
    3. Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Vizeacoumar FJ, et al. Mol Biol Cell, 2004 Feb. PMID 14617799, Free PMC Article
    4. Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Pinsky BA, et al. Mol Cell Biol, 2006 Apr. PMID 16537909, Free PMC Article
    5. Identification of gene products that control lipid droplet size in yeast using a high-throughput quantitative image analysis. Lv X, et al. Biochim Biophys Acta Mol Cell Biol Lipids, 2019 Feb. PMID 30414449

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in peroxisome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in peroxisome organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in peroxisome organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of peroxisome organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum tubular network ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in peroxisomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in peroxisomal membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    peroxisome biogenesis protein
    NP_011518.1
    • Peroxisomal integral membrane protein; involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p; PEX31 has a paralog, PEX30, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      502938..504326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181133.1 → NP_011518.1  TPA: peroxisome biogenesis protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011518.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUE1, P53203
      UniProtKB/TrEMBL
      A0A8H4FBH8, G2WE97, N1P5M8
      Conserved Domains (1) summary
      pfam06398
      Location:51 → 394
      Pex24p; Integral peroxisomal membrane peroxin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53203.1

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