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    IES3 Ies3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850741, updated on 29-Jun-2024

    Summary

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    Gene symbol
    IES3
    Gene description
    Ies3p
    Primary source
    FungiDB:YLR052W
    Locus tag
    YLR052W
    See related
    SGD:S000004042; AllianceGenome:SGD:S000004042; VEuPathDB:YLR052W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in nucleosome mobilization; subtelomeric heterochromatin assembly; and telomere maintenance via recombination. Located in nucleus. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See IES3 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (247201..247953)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Ema19p Neighboring gene Fcf2p Neighboring gene Nrs1p Neighboring gene Osw2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex. Yu EY, et al. Mol Cell Biol, 2007 Aug. PMID 17562861, Free PMC Article
    2. ATP-dependent chromatin remodeling shapes the DNA replication landscape. Vincent JA, et al. Nat Struct Mol Biol, 2008 May. PMID 18408730, Free PMC Article
    3. Genome-wide analysis of the effects of heat shock on a Saccharomyces cerevisiae mutant with a constitutively activated cAMP-dependent pathway. Jones DL, et al. Comp Funct Genomics, 2004. PMID 18629174, Free PMC Article
    4. Structure and functional interactions of INO80 actin/Arp module. Zhang X, et al. J Mol Cell Biol, 2019 May 1. PMID 30388237, Free PMC Article
    5. Identification of Topological Network Modules in Perturbed Protein Interaction Networks. Sardiu ME, et al. Sci Rep, 2017 Mar 8. PMID 28272416, Free PMC Article

    See all (61) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in subtelomeric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in telomere maintenance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in telomere maintenance via recombination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ino80 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Ino80 complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ies3p
    NP_013153.1
    • Subunit of the INO80 chromatin remodeling complex

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      247201..247953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181939.1 → NP_013153.1  TPA: Ies3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013153.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY54, Q12345
      UniProtKB/TrEMBL
      A0A8H4F9T3, A7A0V7, B3LT23, B5VMY7, C7GQN0, G2WIP5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12345.1

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