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    PER33 Per33p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850753, updated on 28-Oct-2024

    Summary

    Official Symbol
    PER33
    Official Full Name
    Per33p
    Primary source
    SGD:S000004054
    Locus tag
    YLR064W
    See related
    AllianceGenome:SGD:S000004054; FungiDB:YLR064W; VEuPathDB:YLR064W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in endoplasmic reticulum tubular network organization and membrane organization. Located in endoplasmic reticulum and nuclear envelope. Orthologous to human TMEM33 (transmembrane protein 33). [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

    See PER33 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (265456..266277)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L22A Neighboring gene 25S rRNA (uracil2843-N3)-methyltransferase Neighboring gene Snd2p Neighboring gene signal peptidase complex subunit SPC3

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in endoplasmic reticulum tubular network organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Per33p
    NP_013165.1
    • Protein that localizes to the endoplasmic reticulum; also associates with the nuclear pore complex; deletion extends chronological lifespan; highly conserved across species, orthologous to human TMEM33 and paralogous to Pom33p; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      265456..266277
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181951.1NP_013165.1  TPA: Per33p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY65, Q12144
      UniProtKB/TrEMBL
      A7A0W9, B3LT34, B5VMZ7, C7GQN9, C8ZD36, G2WIQ6, N1NY22
      Conserved Domains (1) summary
      pfam03661
      Location:24264
      UPF0121; Uncharacterized protein family (UPF0121)