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    IBD2 Ibd2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855557, updated on 28-Oct-2024

    Summary

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    Official Symbol
    IBD2
    Official Full Name
    Ibd2p
    Primary source
    SGD:S000005108
    Locus tag
    YNL164C
    See related
    AllianceGenome:SGD:S000005108; FungiDB:YNL164C; VEuPathDB:YNL164C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in mitotic spindle assembly checkpoint signaling. Predicted to be located in cytoplasm and spindle pole. [provided by Alliance of Genome Resources, Oct 2024]
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    Genomic context

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    See IBD2 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (325265..326320, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Bni5p Neighboring gene uncharacterized protein Neighboring gene GTPase RIA1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption and basic phenotypic analysis of six novel genes from the left arm of chromosome XIV of Saccharomyces cerevisiae. Dueñas E, et al. Yeast, 1999 Jan 15. PMID 10028186
    2. IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae. Hwang HS, et al. Genetics, 2002 Jun. PMID 12072457, Free PMC Article
    3. Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. Haarer B, et al. Genes Dev, 2007 Jan 15. PMID 17167106, Free PMC Article
    4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. Philippsen P, et al. Nature, 1997 May 29. PMID 9169873
    5. Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects. Addinall SG, et al. PLoS Genet, 2011 Apr. PMID 21490951, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic spindle assembly checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitotic spindle assembly checkpoint signaling IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitotic spindle assembly checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ibd2p
    NP_014235.1
    • Component of the BUB2-dependent spindle checkpoint pathway; interacts with Bfa1p and functions upstream of Bub2p and Bfa1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      325265..326320 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183002.1 → NP_014235.1  TPA: Ibd2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014235.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZRR9, D6W118, P53892
      UniProtKB/TrEMBL
      B3LP20, C7GTE1, C8ZG64, G2WLU2, N1P485
      Conserved Domains (1) summary
      COG5271
      Location:71 → 220
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53892.1

    Gene LinkOut

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