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    TIR4 Tir4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854173, updated on 17-May-2024

    Summary

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    Gene symbol
    TIR4
    Gene description
    Tir4p
    Primary source
    FungiDB:YOR009W
    Locus tag
    YOR009W
    See related
    SGD:S000005535; AllianceGenome:SGD:S000005535; VEuPathDB:YOR009W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be a structural constituent of cell wall. Predicted to be involved in fungal-type cell wall organization. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See TIR4 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (344335..345798)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Slg1p Neighboring gene uncharacterized protein Neighboring gene putative GPI-anchored mannoprotein Neighboring gene ATP-binding cassette sterol transporter AUS1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Induction of DAN/TIR yeast cell wall mannoprotein genes in response to high hydrostatic pressure and low temperature. Abe F. FEBS Lett, 2007 Oct 16. PMID 17910955
    2. Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. Abramova N, et al. J Bacteriol, 2001 May. PMID 11292809, Free PMC Article
    3. Impact of Fungal MAPK Pathway Targets on the Cell Wall. Chow J, et al. J Fungi (Basel), 2018 Aug 9. PMID 30096860, Free PMC Article
    4. Identification of genes differentially expressed in association with reduced azole susceptibility in Saccharomyces cerevisiae. Barker KS, et al. J Antimicrob Chemother, 2003 May. PMID 12697649
    5. Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. Hamada K, et al. J Bacteriol, 1999 Jul. PMID 10383953, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables structural constituent of cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tir4p
    NP_014652.1
    • Cell wall mannoprotein; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      344335..345798
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183428.1 → NP_014652.1  TPA: Tir4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014652.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W276, Q12218
      UniProtKB/TrEMBL
      C8ZHX4
      Conserved Domains (1) summary
      pfam00660
      Location:19 → 115
      SRP1_TIP1; Seripauperin and TIP1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12218.1

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