THI72 thiamine transporter [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: THI72
Official Full Name: thiamine transporter
Primary source: SGD:S000005718
Locus tag: YOR192C
See related: AllianceGenome:SGD:S000005718; FungiDB:YOR192C; VEuPathDB:YOR192C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity. Involved in 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport and thiamine transport. Located in cell periphery and fungal-type vacuole. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters, Thi7, Nrt1, and Thi72.
Title: Yeast α-arrestin Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity	IGI Inferred from Genetic Interaction more info	PubMed
enables nucleobase transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in 5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in nitrogen compound transport	IEA Inferred from Electronic Annotation more info
involved_in nucleobase transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in thiamine transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
located_in fungal-type vacuole	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

NP_014835.3

Transporter of thiamine or related compound; contributes to uptake of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (acadesine); shares sequence similarity with Thi7p

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The following sections contain reference sequences that belong to a specific genome build. Explain