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    NCA2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856278, updated on 22-Aug-2024

    Summary

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    Official Symbol
    NCA2
    Primary source
    FungiDB:YPR155C
    Locus tag
    YPR155C
    See related
    SGD:S000006359; AllianceGenome:SGD:S000006359; VEuPathDB:YPR155C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in aerobic respiration and mRNA metabolic process. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (835563..837413, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene May24p Neighboring gene Pin3p Neighboring gene spermine transporter Neighboring gene Tda6p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NCA2, a second nuclear gene required for the control of mitochondrial synthesis of subunits 6 and 8 of ATP synthase in Saccharomyces cerevisiae. Camougrand N, et al. J Mol Biol, 1995 Apr 7. PMID 7723016
    2. NCA3, a nuclear gene involved in the mitochondrial expression of subunits 6 and 8 of the Fo-F1 ATP synthase of S. cerevisiae. Pélissier P, et al. Curr Genet, 1995 Apr. PMID 7586026
    3. Interactomic study on interaction between lipid droplets and mitochondria. Pu J, et al. Protein Cell, 2011 Jun. PMID 21748599, Free PMC Article
    4. Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Zahedi RP, et al. Mol Biol Cell, 2006 Mar. PMID 16407407, Free PMC Article
    5. Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation. Sanchez A, et al. Proc Natl Acad Sci U S A, 2020 Dec 1. PMID 33199619, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in aerobic respiration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial outer membrane HDA PubMed 
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nca2p
    NP_015481.1
    • Protein that regulates expression of Fo-F1 ATP synthase subunits; involved in the regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      835563..837413 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184252.1 → NP_015481.1  TPA: Nca2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015481.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W4F1, Q12374
      UniProtKB/TrEMBL
      B3LKB5, B5VTT9, C7GXU0, C8ZJH9, N1P2G3
      Conserved Domains (1) summary
      pfam08637
      Location:329 → 610
      NCA2; ATP synthase regulation protein NCA2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12374.1

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