U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ptr-19 SSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191751, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ptr-19
    Official Full Name
    SSD domain-containing protein
    Primary source
    WormBase:WBGene00004233
    Locus tag
    CELE_Y39A1B.2
    See related
    AllianceGenome:WB:WBGene00004233
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in molting cycle. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle membrane and plasma membrane. Is expressed in hypodermis; nervous system; and pharynx. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ptr-19 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    15
    Sequence:
    Chromosome: III; NC_003281.10 (10781853..10791176)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Condensin complex subunit 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C-type LECtin Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Kuwabara PE, et al. Genes Dev, 2000 Aug 1. PMID 10921907, Free PMC Article
    2. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article
    3. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    SSD domain-containing protein
    NP_001255085.1
    • Confirmed by transcript evidence
    NP_001255086.1
    • Confirmed by transcript evidence
    NP_001255087.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10781853..10791176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268156.3 → NP_001255085.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255085.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXR9
      Conserved Domains (1) summary
      cl25655
      Location:53 → 858
      Patched; Patched family

    2. NM_001268157.3 → NP_001255086.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255086.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D2N110
      Conserved Domains (1) summary
      cl25655
      Location:53 → 680
      Patched; Patched family

    3. NM_001268158.3 → NP_001255087.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255087.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D2N109
      Conserved Domains (1) summary
      cl25655
      Location:53 → 674
      Patched; Patched family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools