U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cmr4 type III-B CRISPR module RAMP protein Cmr4 [ Pyrococcus furiosus DSM 3638 ]

    Gene ID: 1468995, updated on 24-Oct-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    cmr4
    Gene description
    type III-B CRISPR module RAMP protein Cmr4
    Locus tag
    PF_RS05655
    Gene type
    protein coding
    Organism
    Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
    Lineage
    Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
    Old locus tag
    PF1126
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_003413.1 (1074447..1075334, complement)

    NC_003413.1Genomic Context describing neighboring genes Neighboring gene type I-B CRISPR-associated protein Cas7/Cst2/DevR Neighboring gene type I-B CRISPR-associated protein Cas8b1/Cst1 Neighboring gene type III-B CRISPR module RAMP protein Cmr6 Neighboring gene type III-B CRISPR module-associated protein Cmr5 Neighboring gene CRISPR-associated CARF protein Csx1 Neighboring gene type III-B CRISPR module-associated protein Cmr3 Neighboring gene type III-B CRISPR-associated protein Cas10/Cmr2 Neighboring gene type III-B CRISPR module RAMP protein Cmr1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003413.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex. Ramia NF, et al. Cell Rep, 2014 Dec 11. PMID 25482566, Free PMC Article
    2. Structure of an RNA silencing complex of the CRISPR-Cas immune system. Spilman M, et al. Mol Cell, 2013 Oct 10. PMID 24119404, Free PMC Article
    3. RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Hale CR, et al. Cell, 2009 Nov 25. PMID 19945378, Free PMC Article
    4. Crystal structure of Cmr5 from Pyrococcus furiosus and its functional implications. Park JH, et al. FEBS Lett, 2013 Mar 18. PMID 23370277
    5. Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4. Benda C, et al. Mol Cell, 2014 Oct 2. PMID 25280103

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Four helically packed Cmr4 subunits make up the backbone of the Cmr complex.
      Title: Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex.
    Submit: New GeneRIF Correction

    General protein information

    Go to the top of the page Help
    Preferred Names
    type III-B CRISPR module RAMP protein Cmr4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003413.1 Reference assembly

      Range
      1074447..1075334 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011012266.1 MULTISPECIES: type III-B CRISPR module RAMP protein Cmr4 [Pyrococcus]

      See identical proteins and their annotated locations for WP_011012266.1

      UniProtKB/Swiss-Prot
      Q8U1S9
      UniProtKB/TrEMBL
      A0A5C0XQ24, I6U7E3
      Conserved Domains (1) summary
      TIGR02580
      Location:4 → 280
      cas_RAMP_Cmr4; CRISPR type III-B/RAMP module RAMP protein Cmr4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8U1S9.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Research Materials