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    tiaS tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [ Pyrococcus furiosus DSM 3638 ]

    Gene ID: 1469734, updated on 22-Oct-2024

    Summary

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    Gene symbol
    tiaS
    Gene description
    tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS
    Locus tag
    PF_RS09370
    Gene type
    protein coding
    Organism
    Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
    Lineage
    Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
    Old locus tag
    PF1855
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    Genomic context

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    Sequence:
    NC_003413.1 (1711817..1713091)

    NC_003413.1Genomic Context describing neighboring genes Neighboring gene FAD-dependent oxidoreductase Neighboring gene SDR family oxidoreductase Neighboring gene cyclic pyranopterin monophosphate synthase MoaC Neighboring gene TrkH family potassium uptake protein Neighboring gene pseudo Neighboring gene cysteine synthase family protein Neighboring gene class IV adenylate cyclase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003413.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of tRNA-Modifying Enzyme TiaS and Motions of Its Substrate Binding Zinc Ribbon. Dong J, et al. J Mol Biol, 2018 Oct 19. PMID 30121296
    2. Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea. Ikeuchi Y, et al. Nat Chem Biol, 2010 Apr. PMID 20139989
    3. Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Robb FT, et al. Methods Enzymol, 2001. PMID 11210495
    4. Evidence of recent lateral gene transfer among hyperthermophilic archaea. Diruggiero J, et al. Mol Microbiol, 2000 Nov. PMID 11115105
    5. Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences. Maeder DL, et al. Genetics, 1999 Aug. PMID 10430560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS
    WP_011012995.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003413.1 Reference assembly

      Range
      1711817..1713091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011012995.1 MULTISPECIES: tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [Pyrococcus]

      See identical proteins and their annotated locations for WP_011012995.1

      UniProtKB/TrEMBL
      A0A5C0XU96, I6US00, Q8TZX0
      Conserved Domains (1) summary
      COG1571
      Location:1 → 419
      TiaS; tRNA(Ile2) C34 agmatinyltransferase TiaS [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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