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    PF_RS07365 radical SAM protein [ Pyrococcus furiosus DSM 3638 ]

    Gene ID: 1469346, updated on 22-Oct-2024

    Summary

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    Gene symbol
    PF_RS07365
    Gene description
    radical SAM protein
    Locus tag
    PF_RS07365
    Gene type
    protein coding
    Organism
    Pyrococcus furiosus DSM 3638 (strain: DSM 3638, type-material: type strain of Pyrococcus furiosus)
    Lineage
    Archaea; Methanobacteriati; Methanobacteriota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus
    Old locus tag
    PF1470
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    Genomic context

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    Sequence:
    NC_003413.1 (1375936..1377114, complement)

    NC_003413.1Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene type II/IV secretion system ATPase subunit Neighboring gene alanine--glyoxylate aminotransferase family protein Neighboring gene serine/threonine protein kinase Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003413.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Self-sacrifice in radical S-adenosylmethionine proteins. Booker SJ, et al. Curr Opin Chem Biol, 2007 Oct. PMID 17936058, Free PMC Article
    2. The Radical SAM Superfamily. Frey PA, et al. Crit Rev Biochem Mol Biol, 2008 Jan-Feb. PMID 18307109
    3. Genomic sequence of hyperthermophile, Pyrococcus furiosus: implications for physiology and enzymology. Robb FT, et al. Methods Enzymol, 2001. PMID 11210495
    4. Evidence of recent lateral gene transfer among hyperthermophilic archaea. Diruggiero J, et al. Mol Microbiol, 2000 Nov. PMID 11115105
    5. Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences. Maeder DL, et al. Genetics, 1999 Aug. PMID 10430560, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    radical SAM protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003413.1 Reference assembly

      Range
      1375936..1377114 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_011012617.1 radical SAM protein [Pyrococcus furiosus]

      See identical proteins and their annotated locations for WP_011012617.1

      UniProtKB/TrEMBL
      A0A5C0XQT2, I6V2B5, Q8U0W1
      Conserved Domains (1) summary
      cd01335
      Location:24 → 238
      Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
    Nucleotide Protein
    Heading Accession and Version

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