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    tit1 tRNA isopentenyltransferase [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543065, updated on 18-Sep-2024

    Summary

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    Official Symbol
    tit1
    Official Full Name
    tRNA isopentenyltransferase
    Primary source
    PomBase:SPAC343.15
    Locus tag
    SPOM_SPAC343.15
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mod5
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    Genomic context

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    See tit1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (1673841..1675661)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene glutamyl-tRNA amidotransferase beta subunit Gta2 Neighboring gene ncRNA Neighboring gene translation initiation factor eIF2B beta subunit Neighboring gene WD repeat-containing protein Neighboring gene homoaconitate hydratase Lys2 Neighboring gene ncRNA Neighboring gene SUMO-targeted ubiquitin-protein ligase subunit Rfp2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases. Lamichhane TN, et al. RNA, 2011 Oct. PMID 21873461, Free PMC Article
    2. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. show that TRIT1 can also modify tRNA(Trp)(CCA) consistent with broad recognition similar to Tit1p
      Title: Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables tRNA dimethylallyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in tRNA modification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    tRNA isopentenyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1673841..1675661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018869.3 → NP_593436.1  tRNA isopentenyltransferase [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593436.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UT75
      Conserved Domains (2) summary
      PLN02748
      Location:7 → 427
      PLN02748; tRNA dimethylallyltransferase
      COG0324
      Location:1 → 301
      MiaA; tRNA A37 N6-isopentenylltransferase MiaA [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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