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    exo70 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540127, updated on 22-Aug-2024

    Summary

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    Official Symbol
    exo70
    Primary source
    PomBase:SPBC106.20
    Locus tag
    SPOM_SPBC106.20
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    exo7; SPBC582.02
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    Genomic context

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    See exo70 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003423.3 (417243..419867)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Ppr10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene G2/M B-type cyclin Cdc13 Neighboring gene ncRNA Neighboring gene protein dsh1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast Sec3 and Exo70 are transported on actin cables and localize the exocyst complex to cell poles. Bendezú FO, et al. PLoS One, 2012. PMID 22768263, Free PMC Article
    2. Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex. Tay YD, et al. Cell Rep, 2019 Feb 5. PMID 30726745, Free PMC Article
    3. Rho3p regulates cell separation by modulating exocyst function in Schizosaccharomyces pombe. Wang H, et al. Genetics, 2003 Aug. PMID 12930742, Free PMC Article
    4. Fission yeast sec3 bridges the exocyst complex to the actin cytoskeleton. Jourdain I, et al. Traffic, 2012 Nov. PMID 22891673, Free PMC Article
    5. The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe. Wang H, et al. Mol Biol Cell, 2002 Feb. PMID 11854409, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Orb6 phosphorylation of Sec3 contributes to exocyst function in concert with exocyst protein Exo70.
      Title: Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables phosphatidylinositol-4,5-bisphosphate binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in exocytosis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in intracellular protein transport IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in vesicle tethering involved in exocytosis IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of exocyst IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    exocyst complex subunit Exo70

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      417243..419867
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021078.3 → NP_595170.2  exocyst complex subunit Exo70 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595170.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10339
      Conserved Domains (1) summary
      pfam03081
      Location:253 → 609
      Exo70; Exo70 exocyst complex subunit
    Nucleotide Protein
    Heading Accession and Version

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