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    otu2 OUT family ubiquitin-specific cysteine protease Otu2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542554, updated on 10-Oct-2024

    Summary

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    Official Symbol
    otu2
    Official Full Name
    OUT family ubiquitin-specific cysteine protease Otu2
    Primary source
    PomBase:SPAC1952.03
    Locus tag
    SPOM_SPAC1952.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See otu2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4971166..4972306)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene putative mitochondrial ribosomal protein subunit S18 Neighboring gene ncRNA Neighboring gene Pig-U family GPI transamidase subunit Neighboring gene ribosome biogenesis protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene SAGA complex histone acetyltransferase catalytic subunit Gcn5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity. Kouranti I, et al. PLoS Biol, 2010 Sep 7. PMID 20838651, Free PMC Article
    2. Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex. Egan ED, et al. RNA, 2014 Jun. PMID 24713849, Free PMC Article
    3. Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Rallis C, et al. Sci Rep, 2017 Mar 10. PMID 28281664, Free PMC Article
    4. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ERAD pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    OUT family ubiquitin-specific cysteine protease Otu2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4971166..4972306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020234.3 → NP_594806.2  OUT family ubiquitin-specific cysteine protease Otu2 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0AAN2H679
    Nucleotide Protein
    Heading Accession and Version

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