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    hip3 histone chaperone Hip3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540227, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hip3
    Official Full Name
    histone chaperone Hip3
    Primary source
    PomBase:SPBC31F10.14c
    Locus tag
    SPOM_SPBC31F10.14C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    hir3
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    Genomic context

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    See hip3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3777660..3783327, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene histone chaperone Hip1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene F0-ATPase epsilon subunit Atp15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The HIRA complex subunit Hip3 plays important roles in the silencing of meiosis-specific genes in Schizosaccharomyces pombe. Mizuki F, et al. PLoS One, 2011 Apr 29. PMID 21559379, Free PMC Article
    2. Hip3 interacts with the HIRA proteins Hip1 and Slm9 and is required for transcriptional silencing and accurate chromosome segregation. Greenall A, et al. J Biol Chem, 2006 Mar 31. PMID 16428807
    3. Repression of a large number of genes requires interplay between homologous recombination and HIRA. Misova I, et al. Nucleic Acids Res, 2021 Feb 26. PMID 33511417, Free PMC Article
    4. Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci. Yamane K, et al. Mol Cell, 2011 Jan 7. PMID 21211723, Free PMC Article
    5. Silencing mediated by the Schizosaccharomyces pombe HIRA complex is dependent upon the Hpc2-like protein, Hip4. Anderson HE, et al. PLoS One, 2010 Oct 18. PMID 20976105, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hip3 plays important roles in the control of histone modifications at meiosis-specific gene loci and induces their transcriptional repression
      Title: The HIRA complex subunit Hip3 plays important roles in the silencing of meiosis-specific genes in Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to H3-H4 histone complex chaperone activity IC
    Inferred by Curator
    more info
    		  
    contributes_to nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription elongation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of HIR complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of HIR complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    histone chaperone Hip3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3777660..3783327 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022497.3 → NP_596576.1  histone chaperone Hip3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596576.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P87315
    Nucleotide Protein
    Heading Accession and Version

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