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    ESBP6 Esbp6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855598, updated on 2-Nov-2024

    Summary

    Official Symbol
    ESBP6
    Official Full Name
    Esbp6p
    Primary source
    SGD:S000005069
    Locus tag
    YNL125C
    See related
    AllianceGenome:SGD:S000005069; FungiDB:YNL125C; VEuPathDB:YNL125C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MCH3
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in mitochondrion. Human ortholog(s) of this gene implicated in cataract 47 and familial hyperinsulinemic hypoglycemia 7. Orthologous to several human genes including SLC16A1 (solute carrier family 16 member 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See ESBP6 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (390146..392167, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Far11p Neighboring gene Spc98p Neighboring gene RNA-binding snoRNP assembly protein Neighboring gene Nma111p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Esbp6p
    NP_014274.1
    • Protein with similarity to monocarboxylate permeases; appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      390146..392167 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182963.1NP_014274.1  TPA: Esbp6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014274.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W158, P53918
      UniProtKB/TrEMBL
      A6ZRV9, G2WLY2
      Conserved Domains (1) summary
      cd17352
      Location:212606
      MFS_MCT_SLC16; Monocarboxylate transporter (MCT) family of the Major Facilitator Superfamily of transporters