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    hos2 class 1 histone deacetylase Hos2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543643, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hos2
    Official Full Name
    class 1 histone deacetylase Hos2
    Primary source
    PomBase:SPAC3G9.07c
    Locus tag
    SPOM_SPAC3G9.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    hda1; phd1
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    Genomic context

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    See hos2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (3169671..3171512)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene translation initiation factor eIF2 alpha subunit Neighboring gene ncRNA Neighboring gene chromatin modification-related protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phenylalanine--tRNA (Phe) ligase alpha subunit Frs2 Neighboring gene GTPase-activating protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. phd1+, a histone deacetylase gene of Schizosaccharomyces pombe, is required for the meiotic cell cycle and resistance to trichostatin A. Kim YB, et al. FEBS Lett, 1998 Oct 2. PMID 9781677
    2. HAT-HDAC interplay modulates global histone H3K14 acetylation in gene-coding regions during stress. Johnsson A, et al. EMBO Rep, 2009 Sep. PMID 19633696, Free PMC Article
    3. Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity. Bjerling P, et al. Mol Cell Biol, 2002 Apr. PMID 11884604, Free PMC Article
    4. Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast. Wirén M, et al. EMBO J, 2005 Aug 17. PMID 16079916, Free PMC Article
    5. A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe. Grewal C, et al. Cell Div, 2012 May 4. PMID 22559741, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables histone H4K16 deacetylase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables histone deacetylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone deacetylase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables histone deacetylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    contributes_to transcription corepressor activity IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in epigenetic regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in epigenetic regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of gene expression, epigenetic IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Rpd3L-Expanded complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Rpd3L-Expanded complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Set3 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    NOT is_active_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    class 1 histone deacetylase Hos2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3169671..3171512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019506.3 → NP_594079.1  class 1 histone deacetylase Hos2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594079.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13298
      Conserved Domains (2) summary
      cd11598
      Location:28 → 337
      HDAC_Hos2; Class I histone deacetylases including ScHos2 and SpPhd1
      PTZ00063
      Location:25 → 426
      PTZ00063; histone deacetylase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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