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    hxk1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542634, updated on 22-Aug-2024

    Summary

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    Official Symbol
    hxk1
    Primary source
    PomBase:SPAC24H6.04
    Locus tag
    SPOM_SPAC24H6.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hxk1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (482607..485184, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA replication pre-initiation complex subunit Sld3 Neighboring gene protein tyrosine phosphatase (M phase inducer) Cdc25 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cullin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and kinetic characterization of hexokinase and glucose-6-phosphate dehydrogenase from Schizosaccharomyces pombe. Tsai CS, et al. Biochem Cell Biol, 1998. PMID 9666312
    2. A mutation Ser213/Asn in the hexokinase 1 from Schizosaccharomyces pombe increases its affinity for glucose. Petit T, et al. Biochem Biophys Res Commun, 1998 Oct 29. PMID 9790975
    3. Schizosaccharomyces pombe possesses an unusual and a conventional hexokinase: biochemical and molecular characterization of both hexokinases. Petit T, et al. FEBS Lett, 1996 Jan 8. PMID 8549830
    4. Global coordination of transcriptional control and mRNA decay during cellular differentiation. Amorim MJ, et al. Mol Syst Biol, 2010 Jun 8. PMID 20531409, Free PMC Article
    5. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables D-glucose binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fructokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fructokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables glucokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hexokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables mannokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mannokinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical glycolysis IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in carbohydrate phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fructose metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glucose 6-phosphate metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glucose metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in glycolytic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular glucose homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mannose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mannose metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pentose-phosphate shunt, oxidative branch TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hexokinase 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      482607..485184 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018349.3 → NP_592948.1  hexokinase 1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592948.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09756
      Conserved Domains (3) summary
      COG5026
      Location:10 → 474
      COG5026; Hexokinase [Carbohydrate transport and metabolism]
      pfam00349
      Location:30 → 224
      Hexokinase_1; Hexokinase
      pfam03727
      Location:230 → 466
      Hexokinase_2; Hexokinase
    Nucleotide Protein
    Heading Accession and Version

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