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    prp18 U5 snRNP-associated protein Prp18 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539357, updated on 18-Sep-2024

    Summary

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    Official Symbol
    prp18
    Official Full Name
    U5 snRNP-associated protein Prp18
    Primary source
    PomBase:SPCC126.14
    Locus tag
    SPOM_SPCC126.14
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See prp18 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (2141132..2143550)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene NGG1 interacting factor 3 family protein Neighboring gene tRNA-Asn Neighboring gene SAP128 family histone deacetylase complex subunit Neighboring gene ncRNA Neighboring gene putative signal recognition particle subunit Sec65 Neighboring gene U6 snRNP-associated core protein Neighboring gene ncRNA Neighboring gene wtf meiotic drive antidote Wtf23;wtf meiotic drive poison Wtf23

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Fission Yeast Pre-mRNA-processing Factor 18 (prp18+) Has Intron-specific Splicing Functions with Links to G1-S Cell Cycle Progression. Vijaykrishna N, et al. J Biol Chem, 2016 Dec 30. PMID 27875300, Free PMC Article
    2. The histone variant H2A.Z promotes splicing of weak introns. Nissen KE, et al. Genes Dev, 2017 Apr 1. PMID 28446597, Free PMC Article
    3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
    5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in generation of catalytic spliceosome for second transesterification step IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA cis splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type post-spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    U5 snRNP-associated protein Prp18

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      2141132..2143550
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023448.3 → NP_588457.1  U5 snRNP-associated protein Prp18 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588457.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94406, Q9UTX8
      Conserved Domains (2) summary
      smart00500
      Location:124 → 162
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      pfam02840
      Location:197 → 333
      Prp18; Prp18 domain
    Nucleotide Protein
    Heading Accession and Version

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