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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_030414.1 RefSeqGene
- Range
-
5097..506207
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001040159.2 → NP_001035249.1 testican-3 isoform 1 precursor
See identical proteins and their annotated locations for NP_001035249.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 2.
- Source sequence(s)
-
AC020599, BC003017
- Consensus CDS
-
CCDS34095.1
- UniProtKB/TrEMBL
-
B4DFW5
- Related
- ENSP00000350153.4, ENST00000357545.9
- Conserved Domains (3) summary
-
- smart00280
Location:137 → 180
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:313 → 377
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd16239
Location:198 → 310
- EFh_SPARC_TICN3; EF-hand, extracellular calcium-binding (EC) motif, found in testican-3 (TICN3)
-
NM_001204352.2 → NP_001191281.1 testican-3 isoform 3
See identical proteins and their annotated locations for NP_001191281.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an exon, includes an alternate exon in the 5' coding region, and uses an alternate start codon, compared to variant 2. The encoded isoform (3) is shorter and has a distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AC020599, AK295015, BI603782
- Consensus CDS
-
CCDS56344.1
- UniProtKB/TrEMBL
-
B4DI52
- Related
- ENSP00000411344.2, ENST00000421836.6
- Conserved Domains (4) summary
-
- smart00280
Location:89 → 132
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:265 → 329
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:149 → 268
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:148 → 255
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001204353.1 → NP_001191282.1 testican-3 isoform 4
See identical proteins and their annotated locations for NP_001191282.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR, lacks two exons and uses a downstream, in-frame start codon, compared to variant 2. The encoded isoform (4) has a shorter N-terminus, compared to isoform 2.
- Source sequence(s)
-
AC020599, AK295407
- Consensus CDS
-
CCDS56343.1
- UniProtKB/TrEMBL
-
B4DI52
- Related
- ENSP00000444789.1, ENST00000541354.5
- Conserved Domains (4) summary
-
- smart00280
Location:20 → 63
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:196 → 260
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:80 → 199
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:79 → 186
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001204354.2 → NP_001191283.1 testican-3 isoform 5
See identical proteins and their annotated locations for NP_001191283.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks two consecutive exons and uses a downstream, in-frame start codon, compared to variant 2. The encoded isoform (5) has a shorter N-terminus, compared to isoform 2.
- Source sequence(s)
-
AC020599, AK091078, AK295414
- Consensus CDS
-
CCDS75207.1
- UniProtKB/TrEMBL
- A0A0A0MTJ2, B4DI52
- Related
- ENSP00000441396.2, ENST00000535728.5
- Conserved Domains (4) summary
-
- smart00280
Location:48 → 91
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:224 → 288
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:108 → 227
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:107 → 214
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001204355.2 → NP_001191284.1 testican-3 isoform 6
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) lacks three consecutive coding exons and uses an alternate start codon, compared to variant 2. The encoded isoform (6) is shorter and has a distinct N-terminus, compared to isoform 2.
- Source sequence(s)
-
AC020599, AK295281, BI603782
- UniProtKB/TrEMBL
-
B4DI52
- Conserved Domains (4) summary
-
- smart00280
Location:44 → 87
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:220 → 284
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:104 → 223
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:103 → 210
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001204356.2 → NP_001191285.1 testican-3 isoform 7 precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) lacks two alternate in-frame exons compared to variant 2. The resulting isoform (7) has the same N- and C-termini but is shorter compared to isoform 2.
- Source sequence(s)
-
AC020599, AK296291, BI603782
- Consensus CDS
-
CCDS56346.1
- UniProtKB/TrEMBL
-
B4DFW5
- Related
- ENSP00000426716.1, ENST00000510741.5
- Conserved Domains (3) summary
-
- smart00280
Location:137 → 180
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:273 → 337
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:195 → 276
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
-
NM_001204358.2 → NP_001191287.1 testican-3 isoform 9 precursor
See identical proteins and their annotated locations for NP_001191287.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (9) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 2. The resulting isoform (9, also known as N-TES) has a shorter and distinct C-terminus and lacks an alternate internal segment compared to isoform 2.
- Source sequence(s)
-
AB056866, AC020599
- Consensus CDS
-
CCDS56347.1
- UniProtKB/Swiss-Prot
-
Q9BQ16
- Related
- ENSP00000426177.1, ENST00000512648.5
- Conserved Domains (3) summary
-
- smart00280
Location:137 → 180
- KAZAL; Kazal type serine protease inhibitors
- cd00252
Location:197 → 311
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:196 → 303
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001251967.2 → NP_001238896.1 testican-3 isoform 11 precursor
See identical proteins and their annotated locations for NP_001238896.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (11) lacks four consecutive coding exons but maintains the reading frame, compared to variant 2. The encoded isoform (11) is shorter than isoform 2.
- Source sequence(s)
-
AC020599, AK294637, BI603782
- Consensus CDS
-
CCDS58931.1
- UniProtKB/TrEMBL
-
B4DI52
- Related
- ENSP00000426318.1, ENST00000512681.5
- Conserved Domains (3) summary
-
- cd00191
Location:218 → 282
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:102 → 221
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:101 → 208
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
-
NM_001430594.1 → NP_001417523.1 testican-3 isoform 1 precursor
Status: REVIEWED
- Source sequence(s)
-
AC010103, AC020599, AC023492, AC107210
- Related
- ENSP00000425502.1, ENST00000511269.5
-
NM_016950.3 → NP_058646.2 testican-3 isoform 2 precursor
See identical proteins and their annotated locations for NP_058646.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) encodes the longest isoform (2).
- Source sequence(s)
-
AC020599, AY358973
- Consensus CDS
-
CCDS54817.1
- UniProtKB/Swiss-Prot
- B2R7M7, B3KR67, B4DGK5, B4DHB4, B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, O75705, Q6UW53, Q96Q26, Q9BQ16
- UniProtKB/TrEMBL
-
B4DFW5
- Related
- ENSP00000349677.3, ENST00000357154.7
- Conserved Domains (4) summary
-
- smart00280
Location:140 → 183
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:316 → 380
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:200 → 319
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:199 → 306
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000004.12 Reference GRCh38.p14 Primary Assembly
- Range
-
166733384..167234945 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017008258.2 → XP_016863747.1 testican-3 isoform X3
- UniProtKB/TrEMBL
-
B4DFW5
- Related
- ENSP00000425570.1, ENST00000504953.5
- Conserved Domains (3) summary
-
- smart00280
Location:137 → 180
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:313 → 377
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd16239
Location:198 → 310
- EFh_SPARC_TICN3; EF-hand, extracellular calcium-binding (EC) motif, found in testican-3 (TICN3)
-
XM_011532018.2 → XP_011530320.1 testican-3 isoform X2
See identical proteins and their annotated locations for XP_011530320.1
- UniProtKB/Swiss-Prot
- B2R7M7, B3KR67, B4DGK5, B4DHB4, B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, O75705, Q6UW53, Q96Q26, Q9BQ16
- UniProtKB/TrEMBL
-
B4DFW5
- Related
- ENSP00000420920.1, ENST00000506886.5
- Conserved Domains (4) summary
-
- smart00280
Location:140 → 183
- KAZAL; Kazal type serine protease inhibitors
- cd00191
Location:316 → 380
- TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
- cd00252
Location:200 → 319
- SPARC_EC; SPARC_EC; extracellular Ca2+ binding domain (containing 2 EF-hand motifs) of SPARC and related proteins (QR1, SC1/hevin, testican and tsc-36/FRP). SPARC (BM-40) is a multifunctional glycoprotein, a matricellular protein, that functions to regulate ...
- pfam10591
Location:199 → 306
- SPARC_Ca_bdg; Secreted protein acidic and rich in cysteine Ca binding region
Alternate T2T-CHM13v2.0
Genomic
-
NC_060928.1 Alternate T2T-CHM13v2.0
- Range
-
170090608..170592260 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054350129.1 → XP_054206104.1 testican-3 isoform X3
-
XM_054350128.1 → XP_054206103.1 testican-3 isoform X2
- UniProtKB/Swiss-Prot
- B2R7M7, B3KR67, B4DGK5, B4DHB4, B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, O75705, Q6UW53, Q96Q26, Q9BQ16
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001204359.1: Suppressed sequence
- Description
- NM_001204359.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.