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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_030370.1 RefSeqGene
- Range
-
5051..67960
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001251877.2 → NP_001238806.1 ubiquitin carboxyl-terminal hydrolase 4 isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks several exons and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform c, which is shorter and has a distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
AC121247, BC068017
- Consensus CDS
-
CCDS58832.1
- UniProtKB/Swiss-Prot
-
Q13107
- Related
- ENSP00000400623.1, ENST00000416417.5
- Conserved Domains (2) summary
-
- smart00695
Location:27 → 125
- DUSP; Domain in ubiquitin-specific proteases
- pfam14836
Location:139 → 226
- Ubiquitin_3; Ubiquitin-like domain
-
NM_003363.4 → NP_003354.2 ubiquitin carboxyl-terminal hydrolase 4 isoform a
See identical proteins and their annotated locations for NP_003354.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
AI887410, BC125130, BC125131, DA267618, DB534804
- Consensus CDS
-
CCDS2793.1
- UniProtKB/Swiss-Prot
- A8K6Y0, C9IY91, O43452, O43453, Q08AK8, Q13107
- UniProtKB/TrEMBL
- Q08AK7, Q53FJ3
- Related
- ENSP00000265560.4, ENST00000265560.9
- Conserved Domains (1) summary
-
- cl02553
Location:35 → 923
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
-
NM_199443.3 → NP_955475.1 ubiquitin carboxyl-terminal hydrolase 4 isoform b
See identical proteins and their annotated locations for NP_955475.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
- Source sequence(s)
-
AF017306, AI887410, BC125130, BG717217, DA267618, DB534804
- Consensus CDS
-
CCDS2794.1
- UniProtKB/TrEMBL
-
Q53H56
- Related
- ENSP00000341028.4, ENST00000351842.8
- Conserved Domains (6) summary
-
- smart00695
Location:27 → 125
- DUSP; Domain in ubiquitin-specific proteases
- COG5560
Location:35 → 876
- UBP12; Ubiquitin C-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
- cd02674
Location:729 → 874
- Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- cl02553
Location:255 → 439
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam14533
Location:457 → 520
- USP7_C2; Ubiquitin-specific protease C-terminal
- pfam14836
Location:139 → 226
- Ubiquitin_3; Ubiquitin-like domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
49277144..49340053 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
49305224..49369431 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)