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    GMC1 putative oxidoreductase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852117, updated on 2-Nov-2024

    Summary

    Official Symbol
    GMC1
    Official Full Name
    putative oxidoreductase
    Primary source
    SGD:S000002914
    Locus tag
    YDR506C
    See related
    AllianceGenome:SGD:S000002914; FungiDB:YDR506C; VEuPathDB:YDR506C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable ferroxidase activity. Involved in meiotic cell cycle and synaptonemal complex organization. Predicted to be part of high-affinity iron permease complex. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See GMC1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1459728..1461554, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Spg3p Neighboring gene Psp1p Neighboring gene tRNA-Leu Neighboring gene protein kinase GIN4

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ferroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to iron ion starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in iron ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in meiotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in reductive iron assimilation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptonemal complex organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    part_of high-affinity iron permease complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative oxidoreductase
    NP_010794.3
    • Protein involved in meiotic progression; mutants are delayed in meiotic nuclear division and are defective in synaptonemal complex assembly; possible membrane-localized protein; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1459728..1461554 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180814.3NP_010794.3  TPA: putative oxidoreductase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010794.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTC8, Q04399
      UniProtKB/TrEMBL
      G2WBN4
      Conserved Domains (1) summary
      COG2132
      Location:24547
      SufI; Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA) [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism, Cell wall/membrane/envelope biogenes