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    W01C8.5 DM13 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180836, updated on 2-Nov-2024

    Summary

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    Official Symbol
    W01C8.5
    Official Full Name
    DM13 domain-containing protein
    Primary source
    WormBase:WBGene00020921
    Locus tag
    CELE_W01C8.5
    See related
    AllianceGenome:WB:WBGene00020921
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See W01C8.5 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Sequence:
    Chromosome: X; NC_003284.9 (5694471..5697308, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene SET domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DM13 domain-containing protein
    NP_001123187.1
    • Confirmed by transcript evidence
    NP_508959.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5694471..5697308 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129715.6 → NP_001123187.1  DM13 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123187.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZL4
      Conserved Domains (1) summary
      cl02735
      Location:40 → 76
      DM13; Electron transfer DM13

    2. NM_076558.11 → NP_508959.1  DM13 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508959.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBU2
      Conserved Domains (2) summary
      smart00686
      Location:38 → 146
      DM13; Domain present in fly proteins (CG14681, CG12492, CG6217), worm H06A10.1 and Arabidopsis thaliana MBG8.9
      cl02735
      Location:160 → 264
      DM13; Electron transfer DM13
    Nucleotide Protein
    Heading Accession and Version

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