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    SNX41 Snx41p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852035, updated on 3-Nov-2024

    Summary

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    Official Symbol
    SNX41
    Official Full Name
    Snx41p
    Primary source
    SGD:S000002833
    Locus tag
    YDR425W
    See related
    AllianceGenome:SGD:S000002833; FungiDB:YDR425W; VEuPathDB:YDR425W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables phosphatidylinositol-3-phosphate binding activity. Involved in retrograde transport, endosome to Golgi. Located in endosome. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See SNX41 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1320064..1321941)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Cad1p Neighboring gene dynein light chain Neighboring gene proteasome regulatory particle lid subunit RPN9 Neighboring gene arylformamidase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis. Corcoles-Saez I, et al. Dev Cell, 2018 Aug 20. PMID 30130531
    2. Autophagic clearance of proteasomes in yeast requires the conserved sorting nexin Snx4. Nemec AA, et al. J Biol Chem, 2017 Dec 29. PMID 29109144, Free PMC Article
    3. Membrane protein recycling from the vacuole/lysosome membrane. Suzuki SW, et al. J Cell Biol, 2018 May 7. PMID 29511122, Free PMC Article
    4. Distinct complexes of yeast Snx4 family SNX-BARs mediate retrograde trafficking of Snc1 and Atg27. Ma M, et al. Traffic, 2017 Feb. PMID 28026081, Free PMC Article
    5. Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes. Hettema EH, et al. EMBO J, 2003 Feb 3. PMID 12554655, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol-3-phosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in reticulophagy IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Snx41p
    NP_010713.1
    • Sorting nexin; involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1320064..1321941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180733.1 → NP_010713.1  TPA: Snx41p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010713.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT55, Q04053
      UniProtKB/TrEMBL
      A6ZZ22, B3LFN1, B5VGV9, C8Z5Y6, N1P7G7
      Conserved Domains (1) summary
      COG5391
      Location:87 → 624
      COG5391; Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04053.1

    Gene LinkOut

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