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    SNA2 Sna2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852138, updated on 29-Jun-2024

    Summary

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    Gene symbol
    SNA2
    Gene description
    Sna2p
    Primary source
    FungiDB:YDR525W-A
    Locus tag
    YDR525W-A
    See related
    SGD:S000007236; AllianceGenome:SGD:S000007236; VEuPathDB:YDR525W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in cellular protein catabolic process and endosome transport via multivesicular body sorting pathway. Located in fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SNA2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (1490596..1490835)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Api2p Neighboring gene Rba50p Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Efficient ER exit and vacuole targeting of yeast Sna2p require two tyrosine-based sorting motifs. Renard HF, et al. Traffic, 2010 Jul 1. PMID 20406419
    2. Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting. Reggiori F, et al. EMBO J, 2001 Sep 17. PMID 11566881, Free PMC Article
    3. Genome-wide analysis of the effects of heat shock on a Saccharomyces cerevisiae mutant with a constitutively activated cAMP-dependent pathway. Jones DL, et al. Comp Funct Genomics, 2004. PMID 18629174, Free PMC Article
    4. Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. Kim H, et al. J Biol Chem, 2003 Mar 21. PMID 12524434
    5. Yeast Pmp3p has an important role in plasma membrane organization. De Block J, et al. J Cell Sci, 2015 Oct 1. PMID 26303201

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in fungal-type vacuole membrane HDA PubMed 
    located_in fungal-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Sna2p
    NP_010814.1
    • hypothetical protein; has similarity to Pmp3p, which is involved in cation transport; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1490596..1490835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184329.1 → NP_010814.1  TPA: Sna2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010814.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTE7, P56508
      UniProtKB/TrEMBL
      A0A6A5Q0F3, A6ZZB3, B3LFE4, C7GKV8, C8Z685, G2WBQ3, N1P7S6
      Conserved Domains (1) summary
      COG0401
      Location:1 → 53
      YqaE; Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family [Function unknown]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56508.1

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