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    USV1 Usv1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855871, updated on 2-Nov-2024

    Summary

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    Official Symbol
    USV1
    Official Full Name
    Usv1p
    Primary source
    SGD:S000006151
    Locus tag
    YPL230W
    See related
    AllianceGenome:SGD:S000006151; FungiDB:YPL230W; VEuPathDB:YPL230W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    NSF1
    Summary
    Enables sequence-specific DNA binding activity. Involved in carbon catabolite activation of transcription from RNA polymerase II promoter and cellular response to salt stress. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See USV1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (115312..116487)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene syntaxin Neighboring gene trifunctional fatty acid synthase subunit FAS2 Neighboring gene uncharacterized protein Neighboring gene polynucleotide 5'-phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional analyses of NSF1 in wine yeast using interconnected correlation clustering and molecular analyses. Bessonov K, et al. PLoS One, 2013. PMID 24130853, Free PMC Article
    2. Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. McCammon MT, et al. Mol Biol Cell, 2003 Mar. PMID 12631716, Free PMC Article
    3. Predicting genetic regulatory response using classification. Middendorf M, et al. Bioinformatics, 2004 Aug 4. PMID 15262804
    4. Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Segal E, et al. Nat Genet, 2003 Jun. PMID 12740579
    5. SIR-dependent repression of non-telomeric genes in Saccharomyces cerevisiae? Marchfelder U, et al. Yeast, 2003 Jul 15. PMID 12845605

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. functional analyses of NSF1
      Title: Functional analyses of NSF1 in wine yeast using interconnected correlation clustering and molecular analyses.
    2. The carbon- and NaCl-mediated transcriptional activation of ENA1 is dependent on Nsf1.
      Title: Nsf1/Ypl230w participates in transcriptional activation during non-fermentative growth and in response to salt stress in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in carbon catabolite activation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Usv1p
    NP_015094.1
    • Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis; USV1 has a paralog, RGM1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      115312..116487
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184044.1 → NP_015094.1  TPA: Usv1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015094.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3E0, Q12132
      UniProtKB/TrEMBL
      A6ZW25, B3LKK1, N1NXX4
      Conserved Domains (2) summary
      COG5048
      Location:11 → 389
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:43 → 66
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12132.1

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