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    TEX36 testis expressed 36 [ Homo sapiens (human) ]

    Gene ID: 387718, updated on 3-Apr-2024

    Summary

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    Official Symbol
    TEX36provided by HGNC
    Official Full Name
    testis expressed 36provided by HGNC
    Primary source
    HGNC:HGNC:31653
    See related
    Ensembl:ENSG00000175018 AllianceGenome:HGNC:31653
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C10orf122; bA383C5.1
    Expression
    Restricted expression toward testis (RPKM 3.8) See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    10q26.13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (125576522..125683163, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (126458967..126565578, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (127265091..127371732, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378545 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:127233771-127234271 Neighboring gene uncharacterized LOC124902522 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:127262217-127263416 Neighboring gene TEX36 antisense RNA 1 Neighboring gene uncharacterized LOC102724793 Neighboring gene NANOG hESC enhancer GRCh37_chr10:127273327-127273841 Neighboring gene Sharpr-MPRA regulatory region 5499 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:127350251-127351450 Neighboring gene ALDOA pseudogene 2 Neighboring gene uncharacterized LOC283038 Neighboring gene EDRF1 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4193 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4194 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:127408179-127409161 Neighboring gene erythroid differentiation regulatory factor 1 Neighboring gene EDRF1 antisense RNA 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. Chalasani N, et al. Gastroenterology, 2010 Nov. PMID 20708005, Free PMC Article
    2. Identification of the human testis protein phosphatase 1 interactome. Fardilha M, et al. Biochem Pharmacol, 2011 Nov 15. PMID 21382349
    3. The DNA sequence and comparative analysis of human chromosome 10. Deloukas P, et al. Nature, 2004 May 27. PMID 15164054
    4. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Li X, et al. Mol Syst Biol, 2015 Jan 21. PMID 25609649, Free PMC Article
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ27500, MGC157877, MGC157878

    General protein information

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    Preferred Names
    testis-expressed protein 36
    Names
    testis-expressed sequence 36 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128202.3 → NP_001121674.1  testis-expressed protein 36 isoform a

      See identical proteins and their annotated locations for NP_001121674.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AA977508, AL158835, BC062717
      Consensus CDS
      CCDS44493.1
      UniProtKB/Swiss-Prot
      Q0P5T8, Q5VZQ5
      Related
      ENSP00000357811.3, ENST00000368821.4
      Conserved Domains (1) summary
      pfam15115
      Location:1 → 175
      HDNR; Domain of unknown function with conserved HDNR motif

    2. NM_001318133.2 → NP_001305062.1  testis-expressed protein 36 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate 3' terminal exon, and it thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
      Source sequence(s)
      AL158835, AL805915, BC062717, BC127767, BX336391, BX390366
      Consensus CDS
      CCDS81521.1
      UniProtKB/TrEMBL
      A0PJZ8, E9PJL2
      Related
      ENSP00000431764.1, ENST00000532135.5
      Conserved Domains (1) summary
      pfam15115
      Location:1 → 88
      HDNR; Domain of unknown function with conserved HDNR motif

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      125576522..125683163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005269817.5 → XP_005269874.1  testis-expressed protein 36 isoform X1

      UniProtKB/TrEMBL
      E9PR91
      Conserved Domains (1) summary
      pfam15115
      Location:1 → 90
      HDNR; Domain of unknown function with conserved HDNR motif

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      126458967..126565578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054365903.1 → XP_054221878.1  testis-expressed protein 36 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5VZQ5.1 GenPept UniProtKB/Swiss-Prot:Q5VZQ5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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