FKS3 putative 1,3-beta-D-glucan synthase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: FKS3
Official Full Name: putative 1,3-beta-D-glucan synthase
Primary source: SGD:S000004923
Locus tag: YMR306W
See related: AllianceGenome:SGD:S000004923; FungiDB:YMR306W; VEuPathDB:YMR306W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable 1,3-beta-D-glucan synthase activity. Involved in ascospore wall assembly. Located in endoplasmic reticulum and mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See FKS3 in Genome Data Viewer

Location:: chromosome: XIII

Exon count:: 1

Sequence:: Chromosome: XIII; NC_001145.3 (881159..886516)

Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables 1,3-beta-D-glucan synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables 1,3-beta-D-glucan synthase activity	IEA Inferred from Electronic Annotation more info
enables 1,3-beta-D-glucan synthase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in (1->3)-beta-D-glucan biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in (1->3)-beta-D-glucan biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in ascospore wall assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell wall organization	IEA Inferred from Electronic Annotation more info
involved_in fungal-type cell wall polysaccharide biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of 1,3-beta-D-glucan synthase complex	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative 1,3-beta-D-glucan synthase

NP_014036.1

EC 2.4.1.34

Protein involved in spore wall assembly; has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001145.3 Reference assembly

Range

881159..886516

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001182817.1 → NP_014036.1 TPA: putative 1,3-beta-D-glucan synthase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_014036.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6W0D3, Q04952

UniProtKB/TrEMBL

B3LMJ4, C7GPV7, C8ZFH5, G2WL15, N1NZ80

Conserved Domains (2) summary

pfam02364
Location:694 → 1542

Glucan_synthase; 1,3-beta-glucan synthase component

pfam14288
Location:182 → 290

FKS1_dom1; 1,3-beta-glucan synthase subunit FKS1, domain-1