DTD1 D-tyrosyl-tRNA(Tyr) deacylase [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: DTD1
Official Full Name: D-tyrosyl-tRNA(Tyr) deacylase
Primary source: SGD:S000002378
Locus tag: YDL219W
See related: AllianceGenome:SGD:S000002378; FungiDB:YDL219W; VEuPathDB:YDL219W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables D-leucyl-tRNA(Leu) deacylase activity and D-tyrosyl-tRNA(Tyr) deacylase activity. Involved in D-leucine catabolic process; D-tyrosine catabolic process; and tRNA metabolic process. Located in cytoplasm. Orthologous to human DTD1 (D-aminoacyl-tRNA deacylase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables D-aminoacyl-tRNA deacylase activity	IEA Inferred from Electronic Annotation more info
enables D-leucyl-tRNA(Leu) deacylase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables D-tyrosyl-tRNA(Tyr) deacylase activity	IBA Inferred from Biological aspect of Ancestor more info
enables D-tyrosyl-tRNA(Tyr) deacylase activity	IEA Inferred from Electronic Annotation more info
enables D-tyrosyl-tRNA(Tyr) deacylase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables tRNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in D-leucine catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in D-tyrosine catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in aminoacyl-tRNA metabolism involved in translational fidelity	IEA Inferred from Electronic Annotation more info
involved_in tRNA metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_010062.1

D-Tyr-tRNA(Tyr) deacylase; functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes

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