MKT1 Mkt1p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: MKT1
Official Full Name: Mkt1p
Primary source: SGD:S000005029
Locus tag: YNL085W
See related: AllianceGenome:SGD:S000005029; FungiDB:YNL085W; VEuPathDB:YNL085W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable 5'-flap endonuclease activity. Involved in cellular response to DNA damage stimulus. Located in P-body and nuclear periphery. Part of polysome. [provided by Alliance of Genome Resources, Apr 2022]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome XIV - NC_001146.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

MKT1 alleles regulate stress responses through posttranscriptional modulation of Puf3 targets in budding yeast.
Title: MKT1 alleles regulate stress responses through posttranscriptional modulation of Puf3 targets in budding yeast.
A tps1Delta persister-like state in Saccharomyces cerevisiae is regulated by MKT1.
Title: A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1.
MKT1, SWS2, and APJ1 are associated with high ethanol tolerance in Saccharomyces cerevisiae.
Title: Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis.
In a low-glucose environment, MDS3e and MKT1e interacted positively to confer a fitness advantage.
Title: Cellular effects and epistasis among three determinants of adaptation in experimental populations of Saccharomyces cerevisiae.
Studies show that by using CYS4 as a covariate and conducted both single- and combined-cross linkage mapping, AQY1 and MKT1 were found to have drug-specific and background-dependent effects.
Title: A combined-cross analysis reveals genes with drug-specific and background-dependent effects on drug sensitivity in Saccharomyces cerevisiae.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA endonuclease activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables mRNA 3'-UTR binding	IBA Inferred from Biological aspect of Ancestor more info
enables nuclease activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA damage response	IEA Inferred from Electronic Annotation more info
involved_in DNA damage response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in DNA metabolic process	IEA Inferred from Electronic Annotation more info
involved_in regulation of translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in P-body	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	HDA more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic stress granule	HDA more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in nuclear periphery	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

NP_014314.3

Protein similar to nucleases that forms a complex with Pbp1p; complex may mediate posttranscriptional regulation of HO; involved in propagation of M2 dsRNA satellite of L-A virus; allelic variation affects mitochondrial genome stability, drug resistance, and more; forms cytoplasmic foci upon DNA replication stress; localization to P-bodies under ethanol stress differs between strains

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain