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    SCW10 putative family 17 glucosidase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855352, updated on 2-Nov-2024

    Summary

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    Official Symbol
    SCW10
    Official Full Name
    putative family 17 glucosidase
    Primary source
    SGD:S000004921
    Locus tag
    YMR305C
    See related
    AllianceGenome:SGD:S000004921; FungiDB:YMR305C; VEuPathDB:YMR305C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable glucan endo-1,3-beta-D-glucosidase activity. Involved in conjugation with cellular fusion. Located in extracellular region and fungal-type cell wall. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See SCW10 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (879063..880232, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase ADH2 Neighboring gene ubiquitin-specific protease UBP15 Neighboring gene putative 1,3-beta-D-glucan synthase Neighboring gene 1,3-beta-glucanosyltransferase GAS1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Aspartic Protease Yps3p and Cell Wall Glucanase Scw10p Are Novel Determinants That Enhance the Secretion of the Antitumor Triterpenoid GA-HLDOA in Saccharomyces cerevisiae. Fang Y, et al. ACS Synth Biol, 2022 Sep 16. PMID 35969118
    2. New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating. Cappellaro C, et al. J Bacteriol, 1998 Oct. PMID 9748433, Free PMC Article
    3. Scw10p, a cell-wall glucanase/transglucosidase important for cell-wall stability in Saccharomyces cerevisiae. Sestak S, et al. Microbiology (Reading), 2004 Oct. PMID 15470100
    4. Binding assay for incorporation of alkali-extractable proteins in the Saccharomyces cerevisiae cell wall. Teparić R, et al. Yeast, 2007 Apr. PMID 17315268
    5. Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling. Zeitlinger J, et al. Cell, 2003 May 2. PMID 12732146

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables glucan endo-1,3-beta-D-glucosidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glucosidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in conjugation with cellular fusion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type cell wall IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative family 17 glucosidase
    NP_014035.1
    • Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p; SWC10 has a paralog, SCW4, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      879063..880232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182815.1 → NP_014035.1  TPA: putative family 17 glucosidase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014035.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0D2, Q04951
      UniProtKB/TrEMBL
      A6ZN21, B3LMJ3, C7GPV8, C8ZFH4, N1P635
      Conserved Domains (1) summary
      COG5309
      Location:92 → 389
      Scw11; Exo-beta-1,3-glucanase, GH17 family [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04951.1

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