VAN1 Van1p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: VAN1
Official Full Name: Van1p
Primary source: SGD:S000004583
Locus tag: YML115C
See related: AllianceGenome:SGD:S000004583; FungiDB:YML115C; VEuPathDB:YML115C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: LDB13; VRG7; VRG8
Summary: Contributes to alpha-1,6-mannosyltransferase activity. Involved in cell wall mannoprotein biosynthetic process and protein N-linked glycosylation. Part of mannan polymerase complex. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

These results provide further information on the role of M-Pol I and its subunits Mnn9 and Van1 in mannan biosynthesis.
Title: Expression and purification of recombinant M-Pol I from Saccharomyces cerevisiae with alpha-1,6 mannosylpolymerase activity.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to alpha-1,6-mannosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to alpha-1,6-mannosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in cell wall mannoprotein biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in cell wall mannoprotein biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation	IDA Inferred from Direct Assay more info	PubMed
involved_in protein N-linked glycosylation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
part_of mannan polymerase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mannan polymerase complex	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_013592.1

Component of the mannan polymerase I; complex contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant