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    VMA6 H(+)-transporting V0 sector ATPase subunit d [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851168, updated on 2-Nov-2024

    Summary

    Official Symbol
    VMA6
    Official Full Name
    H(+)-transporting V0 sector ATPase subunit d
    Primary source
    SGD:S000004439
    Locus tag
    YLR447C
    See related
    AllianceGenome:SGD:S000004439; FungiDB:YLR447C; VEuPathDB:YLR447C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to proton-transporting ATPase activity, rotational mechanism. Involved in vacuolar transport. Located in fungal-type vacuole membrane. Orthologous to human ATP6V0D1 (ATPase H+ transporting V0 subunit d1) and ATP6V0D2 (ATPase H+ transporting V0 subunit d2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See VMA6 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (1026856..1027893, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Gmc2p Neighboring gene hexokinase Neighboring gene ribosomal 60S subunit protein L6B Neighboring gene peptidylprolyl isomerase FPR4

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vacuolar acidification IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vacuolar transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vacuolar transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in vacuolar transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in fungal-type vacuole membrane HDA PubMed 
    is_active_in fungal-type vacuole membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in fungal-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proton-transporting V-type ATPase, V0 domain IEA
    Inferred from Electronic Annotation
    more info
     
    located_in vacuolar membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of vacuolar proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of vacuolar proton-transporting V-type ATPase, V0 domain TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in vacuole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    H(+)-transporting V0 sector ATPase subunit d
    NP_013552.3
    • Subunit d of the V0 integral membrane domain of V-ATPase; part of the electrogenic proton pump found in the endomembrane system; required for V1 domain assembly on the vacuolar membrane; the V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase) has five subunits

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      1026856..1027893 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182335.3NP_013552.3  TPA: H(+)-transporting V0 sector ATPase subunit d [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013552.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ81, P32366
      UniProtKB/TrEMBL
      A7A1W6, B3RHV5, B5VNY4, C7GSK9, C8ZE54, G2WJQ8, N1NZY4
      Conserved Domains (1) summary
      COG1527
      Location:1345
      NtpC; Archaeal/vacuolar-type H+-ATPase subunit C/Vma6 [Energy production and conversion]