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    COX26 Cox26p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 3799970, updated on 18-Sep-2024

    Summary

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    Official Symbol
    COX26
    Official Full Name
    Cox26p
    Primary source
    SGD:S000113555
    Locus tag
    YDR119W-A
    See related
    AllianceGenome:SGD:S000113555; FungiDB:YDR119W-A; VEuPathDB:YDR119W-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrial respirasome. Part of mitochondrial respiratory chain complex IV. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See COX26 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (691014..691214)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene anaphase promoting complex subunit 4 Neighboring gene Vba4p Neighboring gene tRNA (guanine26-N2)-dimethyltransferase Neighboring gene DNA polymerase epsilon noncatalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Supercomplex-associated Cox26 protein binds to cytochrome c oxidase. Strecker V, et al. Biochim Biophys Acta, 2016 Jul. PMID 27091403, Free PMC Article
    2. Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance. Berndtsson J, et al. EMBO Rep, 2020 Dec 3. PMID 33016568, Free PMC Article
    3. Mutational Analysis of the QRRQ Motif in the Yeast Hig1 Type 2 Protein Rcf1 Reveals a Regulatory Role for the Cytochrome c Oxidase Complex. Garlich J, et al. J Biol Chem, 2017 Mar 31. PMID 28167530, Free PMC Article
    4. A three-way proteomics strategy allows differential analysis of yeast mitochondrial membrane protein complexes under anaerobic and aerobic conditions. Helbig AO, et al. Proteomics, 2009 Oct. PMID 19750512
    5. Cox26 is a novel stoichiometric subunit of the yeast cytochrome c oxidase. Levchenko M, et al. Biochim Biophys Acta, 2016 Jul. PMID 27083394

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of respiratory chain complex IV IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cox26p
    NP_001032575.1
    • Subunit of cytochrome C oxidase complex; stabilizes or regulates formation of respiratory chain supercomplexes composed of Complex III (ubiquinol-cytochrome c reductase) and Complex IV (cytochrome c oxidase)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      691014..691214
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184681.1 → NP_001032575.1  TPA: Cox26p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_001032575.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSA5, Q2V2P9
      UniProtKB/TrEMBL
      A6ZY81, B3LGF7, C7GIM7, G2WAM1, N1P6C3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2V2P9.1

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